Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.37 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30699913 | 0.89 | MGLL (0.41) | HSD11B1MGLLGAACCNT1CDK9 | |
| SCHEMBL30700211 | 0.76 | MGLL (0.40) | MGLLGAACCNT1CDK9OXTR | |
| SCHEMBL24095446 | 0.76 | MGLL (0.61) | MGLL | |
| SCHEMBL25785175 | 0.76 | MGLL (0.61) | MGLL | |
| SCHEMBL24095488 | 0.76 | MGLL (0.61) | MGLL | |
| SCHEMBL30699875 | 0.76 | MGLL (0.42) | MGLLGAACCNT1CDK9OXTR | |
| SCHEMBL30700691 | 0.76 | MGLL (0.42) | MGLLGAACCNT1CDK9OXTR | |
| SCHEMBL30700304 | 0.75 | MGLL (0.44) | HSD11B1MGLLVNN1 | |
| SCHEMBL27288284 | 0.75 | MGLL (0.44) | HSD11B1MGLLVNN1 | |
| SCHEMBL23365170 | 0.74 | HRH1 (0.48) | HSD11B1OXTRAVPR1AUTS2RSCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |