Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 13/20 | 0.42 |
| ▸ | OXTR | P30559 | 2/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700691 | 1.00 | MGLL (0.42) | MGLLOXTRAVPR1AGAACCNT1 | |
| SCHEMBL30699995 | 0.84 | MGLL (0.38) | MGLL | |
| SCHEMBL30699913 | 0.78 | MGLL (0.41) | MGLLOXTRAVPR1AGAACCNT1 | |
| SCHEMBL24095477 | 0.78 | MGLL (0.56) | MGLL | |
| SCHEMBL30700320 | 0.78 | MGLL (0.40) | MGLLOXTRAVPR1AGAA | |
| SCHEMBL30700429 | 0.76 | LIPE (0.35) | — | |
| SCHEMBL30700211 | 0.76 | MGLL (0.40) | MGLLOXTRAVPR1AGAACCNT1 | |
| SCHEMBL27288289 | 0.76 | HSD11B1 (0.42) | MGLLOXTRAVPR1AGAACCNT1 | |
| SCHEMBL30700576 | 0.71 | MGLL (0.41) | MGLLOXTRAVPR1A | |
| SCHEMBL30700887 | 0.71 | MGLL (0.40) | MGLLGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |