Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 2/20 | 0.43 |
| ▸ | FNTB | P49356 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12095977 | 0.86 | AKR1B1 (0.52) | TSHRALDH1A1AKR1B1GPR84PPARG | |
| SCHEMBL3103935 | 0.82 | GPR84 (0.52) | TSHRALDH1A1AKR1B1GPR84PPARG | |
| SCHEMBL8089512 | 0.82 | CES1 (0.48) | TSHRALDH1A1AKR1B1GPR84PPARG | |
| SCHEMBL88045 | 0.82 | CES1 (0.48) | TSHRALDH1A1AKR1B1GPR84PPARG | |
| SCHEMBL9189325 | 0.81 | ALDH1A1 (0.46) | TSHRALDH1A1AKR1B1GPR84PPARG | |
| SCHEMBL9167905 | 0.81 | GPR84 (0.50) | TSHRALDH1A1AKR1B1GPR84PPARG | |
| SCHEMBL3979241 | 0.78 | CES1 (0.44) | TSHRALDH1A1AKR1B1GPR84PPARG | |
| SCHEMBL28694016 | 0.77 | AKR1B1 (0.46) | TSHRALDH1A1AKR1B1GPR84PPARG | |
| SCHEMBL2940335 | 0.77 | CES1 (0.40) | TSHRALDH1A1AKR1B1FNTAFNTB | |
| Acetic Acid SCHEMBL5172555 | 0.76 | AKR1B1 (0.50) | TSHRALDH1A1AKR1B1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1037177-C | Noel 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them | AMERICAN CYANAMID CO (US) | 1998-01-28 | — | — | CN | disclosed |
| CN-1034329-C | Novel 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them | AMERICAN CYANAMID CO (US) | 1997-03-26 | — | — | CN | disclosed |
| CN-1034332-C | Process for preparing 2-substituted alkyl-3-carboxy carbapenems as antibiotics | AMERICAN CYANAMID CO (US) | 1997-03-26 | — | — | CN | disclosed |