Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909628 | 0.79 | ALDH1A1 (0.50) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL5924701 | 0.78 | PDK2 (0.58) | SLC6A4SLC6A3LMNAMEN1KMT2A | |
| SCHEMBL2409870 | 0.77 | TSHR (0.49) | SLC6A4SLC6A3LMNAALDH1A1HTT | |
| SCHEMBL2437425 | 0.77 | TSHR (0.49) | SLC6A4SLC6A3LMNAALDH1A1HTT | |
| SCHEMBL21037806 | 0.77 | SLC6A3 (0.52) | SLC6A4SLC6A3LMNAMEN1KMT2A | |
| SCHEMBL21037808 | 0.77 | SLC6A3 (0.52) | SLC6A4SLC6A3LMNAMEN1KMT2A | |
| SCHEMBL27838174 | 0.75 | DHODH (0.53) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL20806423 | 0.75 | SLC6A3 (0.54) | SLC6A4SLC6A3LMNAMEN1KMT2A | |
| SCHEMBL8500735 | 0.75 | SLC6A3 (0.54) | SLC6A4SLC6A3LMNAMEN1KMT2A | |
| SCHEMBL28822988 | 0.75 | ERN1 (0.52) | LMNAMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1009831-B | PROCESS FOR PREPARING HETEROCYCLE-OXO-2,3-DIAZANAPHTHYL-ACETIC ACID | PFIZER (US) | 1990-10-03 | — | — | CN | disclosed |
| CN-86108308-A | Heterocycle oxo-2 guanidine-acetic acid | — | 1987-07-15 | — | — | CN | disclosed |