Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 4/20 | 0.58 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | BMP4 | P12644 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067917 | 0.91 | KDM4E (0.57) | TGFBR1GRM4KDM4ENPC1MAPT | |
| SCHEMBL17177705 | 0.87 | TGFBR1 (0.58) | TGFBR1GRM4KDM4ERAB9ANPC1 | |
| SCHEMBL1227713 | 0.85 | CYP1A2 (0.60) | TGFBR1GRM4KDM4ERAB9ANPC1 | |
| SCHEMBL29699887 | 0.85 | CYP1A2 (0.60) | TGFBR1GRM4KDM4ERAB9ANPC1 | |
| SCHEMBL27917128 | 0.85 | CYP1A2 (0.60) | TGFBR1GRM4KDM4ERAB9ANPC1 | |
| SCHEMBL30487734 | 0.83 | CYP1A2 (0.58) | TGFBR1GRM4KDM4ERAB9ANPC1 | |
| SCHEMBL7918743 | 0.82 | MAPT (0.56) | TGFBR1GRM4KDM4ERAB9ANPC1 | |
| SCHEMBL27566240 | 0.82 | TGFBR1 (0.53) | TGFBR1GRM4KDM4ERAB9ANPC1 | |
| SCHEMBL12382123 | 0.81 | BMP4 (0.48) | TGFBR1GRM4KDM4ERAB9ANPC1 | |
| SCHEMBL27491176 | 0.80 | CYP1A2 (0.49) | TGFBR1GRM4KDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1028754-C | process for preparing quinoline derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-06-07 | — | — | CN | disclosed |
| CN-1039416-A | Quinoline and preparation thereof and purposes | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1990-02-07 | — | — | CN | disclosed |