SCHEMBL2729013

SCHEMBL2729013

NC(=O)C1CC=NO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11202159 0.70
SCHEMBL2534271 0.64
SCHEMBL33498 0.62
SCHEMBL7519504 0.62
SCHEMBL7525914 0.62
SCHEMBL7855682 0.62
SCHEMBL25661144 0.60 GABRR1 (0.36)
SCHEMBL25661145 0.60 GABRR1 (0.36)
SCHEMBL7021378 0.59
Bicarbonate SCHEMBL5246269 0.58 ACHE (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104797577-B Weeding and the formamide of 3 heteroaryl isoxazoline 5 and the thioamides of 3 heteroaryl isoxazoline 5 of Fungicidally active 拜尔农作物科学股份公司 2018-01-12 CN claimed
CN-104797577-A Herbicidally and fungicidally active 3-heteroaryl-isoxazoline-5-carboxamides and 3-heteroaryl-isoxazoline-5-thioamides BAYER CROPSCIENCE AG 2015-07-22 CN claimed
EP-2632906-A1 OXAZOLINE AND ISOXAZOLINE DERIVATIVES AS CRAC MODULATORS Lupin Limited (IN) 2013-09-04 EP claimed
WO-2012056478-A1 OXAZOLE AND ISOXAZOLE CRAC MODULATORS LUPIN LIMITED (IN) 2012-05-03 WO claimed
WO-2006016237-A2 HETEROCYCLIC DERIVATIVES AS ANTI-INFLAMMATORY AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-02-16 WO claimed
US-12570675-B2 Boronic acid compounds LG CHEM, LTD. (KR) 2026-03-10 US disclosed
CN-115710195-B Trifluoro-olefine compound with nematicidal activity and its preparation method and use 华东理工大学 2025-02-14 CN disclosed
EP-3668845-B1 HERBICIDALLY ACTIVE 3-PHENYL-5-TRIFLUORMETHYLISOXAZOLIN-5-CARBOXAMIDES OF CYCLOPENTYL CARBOXYLIC ACIDS AND ESTERS BAYER AG (DE) 2024-06-26 EP disclosed
US-20240101579-A1 BORONIC ACID COMPOUNDS LG CHEM, LTD. (KR) 2024-03-28 US disclosed
CN-111164077-B Herbicidal 3-phenyl-5-trifluoromethyl isoxazoline-5-carboxamides of cyclopentylcarboxylic acids and esters thereof 拜耳公司 2023-12-19 CN disclosed
CN-111868042-B Herbicidal 3-phenylisoxazoline-5-carboxamides of cyclopentylcarboxylic acid derivatives 拜耳公司 2023-12-05 CN disclosed
CN-116887827-A Compounds and methods for modulating FXR 拓臻制药公司 2023-10-13 CN disclosed
WO-2018228985-A1 HERBICIDALLY ACTIVE 3-PHENYLISOXAZOLINE-5-CARBOXAMIDES OF TETRAHYDRO AND DIHYDROFURAN CARBOXYLIC ACIDS AND ESTERS BAYER AKTIENGESELLSCHAFT (DE) 2018-12-20 WO disclosed
WO-2018228986-A1 HERBICIDALLY ACTIVE 3-PHENYLISOXAZOLINE-5-CARBOXAMIDES OF TETRAHYDRO AND DIHYDROFURAN CARBOXAMIDES BAYER AKTIENGESELLSCHAFT (DE) 2018-12-20 WO disclosed
CN-104797564-B The 3- phenyl-isoxazole oxazoline -5- thioamides of the 3- phenyl-isoxazoles oxazoline -5- formamides and 5- epoxides of weeding and antifungal 5- epoxides-substituted-substituted 拜尔农作物科学股份公司 2018-05-04 CN disclosed
CN-104797577-B Weeding and the formamide of 3 heteroaryl isoxazoline 5 and the thioamides of 3 heteroaryl isoxazoline 5 of Fungicidally active 拜尔农作物科学股份公司 2018-01-12 CN disclosed
CN-104812739-B The 3 phenyl-isoxazole oxazoline derivatives with herbicide effect 拜尔农作物科学股份公司 2017-12-12 CN disclosed
WO-2015147022-A1 ISOXAZOLIN-5-CARBOXAMIDE COMPOUND AND PESTICIDE 日本曹達株式会社 2015-10-01 WO disclosed
CN-104797577-A Herbicidally and fungicidally active 3-heteroaryl-isoxazoline-5-carboxamides and 3-heteroaryl-isoxazoline-5-thioamides BAYER CROPSCIENCE AG 2015-07-22 CN disclosed
US-7241779-B2 Fused pyrrolocarbazoles CEPHALON, INC. (US) 2007-07-10 US disclosed