Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | AOC1 | P19801 | 4/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6628774 | 0.77 | TKT (0.39) | GPR119ALDH1A1KDM4ESIRT3TDP1 | |
| SCHEMBL873728 | 0.75 | CYP2E1 (0.49) | TDP1AOC1AOC3LOXL2TRPA1 | |
| SCHEMBL22493354 | 0.74 | HRH4 (0.37) | GPR119ALDH1A1KDM4EMAPTNOTUM | |
| SCHEMBL12870192 | 0.73 | AOC1 (0.36) | GPR119ALDH1A1KDM4EMAPTSIRT3 | |
| SCHEMBL14945019 | 0.73 | TAAR1 (0.52) | SIRT3TDP1AOC1AOC3LOXL2 | |
| SCHEMBL1448227 | 0.72 | — | — | |
| SCHEMBL18924363 | 0.72 | TDP1 (0.43) | ALDH1A1KDM4EMAPTTDP1AOC1 | |
| SCHEMBL21983945 | 0.72 | TAAR1 (0.50) | ALDH1A1KDM4ENOTUMTRPA1 | |
| SCHEMBL23599089 | 0.71 | NPSR1 (0.53) | SIRT3TDP1NOTUM | |
| SCHEMBL18888245 | 0.70 | TDP1 (0.39) | ALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105364-A1 | HETEROCYCLIC INHIBITORS OF CDC-LIKE KINASES | CURADEV PHARMA LTD (GB) | 2024-05-23 | — | — | WO | disclosed |