Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10372180 | 0.89 | PPARG (0.40) | KDM4EPPARGPPARAALDH1A1SMN1; SMN2 | |
| SCHEMBL10372531 | 0.81 | EDNRA (0.41) | KDM4EALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL27290346 | 0.78 | KLKB1 (0.45) | KDM4EFGFR1SRCFGFR2FGFR4 | |
| SCHEMBL10372057 | 0.77 | ADCY1 (0.36) | KDM4EPPARGPPARAALDH1A1HTT | |
| SCHEMBL10373608 | 0.77 | EDNRA (0.40) | KDM4EALDH1A1SMN1; SMN2HTTNPC1 | |
| SCHEMBL27280518 | 0.77 | NR4A2 (0.44) | KDM4EALDH1A1SMN1; SMN2HTTNPC1 | |
| SCHEMBL10373898 | 0.72 | EDNRA (0.51) | KDM4EALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL9434171 | 0.71 | KMT2A (0.40) | KDM4EALDH1A1SMN1; SMN2NPC1GAA | |
| SCHEMBL10373085 | 0.71 | ALDH1A1 (0.44) | KDM4EALDH1A1SMN1; SMN2NPC1MAPT | |
| SCHEMBL27283282 | 0.70 | KDM4E (0.43) | KDM4EFGFR1SRCFGFR2FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1007153-B | PREPN. OF BENZOTHIOPHENES AND BENZOFURANS HAVING ANTIALLERGY ACTIVITY | WARNER LAMBERT CO (US) | 1990-03-14 | — | — | CN | disclosed |
| CN-85109587-A | Have the new benzothiophene kind of antiallergic activity and the preparation method of benzofuran compounds | — | 1986-12-17 | — | — | CN | disclosed |