Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10255243 | 0.86 | APP (0.44) | ROCK2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL15762727 | 0.84 | ALDH1A1 (0.48) | ROCK2MEN1KMT2AKDM4EADRB2 | |
| SCHEMBL13746231 | 0.81 | ROCK2 (0.42) | ROCK2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9917266 | 0.81 | RXFP1 (0.44) | ROCK2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL23347013 | 0.81 | ROCK2 (0.42) | ROCK2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL23193237 | 0.81 | ROCK2 (0.45) | ROCK2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL25448141 | 0.81 | ROCK2 (0.42) | ROCK2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL21671263 | 0.80 | MEN1 (0.56) | ROCK2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL19491612 | 0.80 | KMT2A (0.58) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL19154800 | 0.80 | ROCK2 (0.41) | ROCK2MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129756-A1 | SITE-SPECIFIC ENGINEERED CYSTEINE ANTIBODY DRUG CONJUGATES | SEAGEN INC. (US) | 2024-06-20 | — | — | WO | disclosed |