Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4566612 | 0.86 | CYP19A1 (0.45) | KMT2ACYP19A1MAPTKDM4ENPC1 | |
| SCHEMBL30155019 | 0.74 | CA1 (0.51) | CYP19A1MAPTKDM4ENPC1HDAC1 | |
| SCHEMBL1650589 | 0.74 | CA1 (0.51) | CYP19A1MAPTKDM4ENPC1HDAC1 | |
| SCHEMBL8990514 | 0.74 | EPHX2 (0.53) | CYP19A1MAPTKDM4EHDAC1HDAC8 | |
| SCHEMBL9275073 | 0.73 | CYP19A1 (0.47) | CYP19A1MAPTKDM4EMAOAHDAC1 | |
| Phenyl Phenylmethanesulfonate SCHEMBL6912876 | 0.73 | KMT2A (1.00) | KMT2AHTTFAAHCA1CA2 | |
| SCHEMBL27851812 | 0.72 | KMT2A (0.64) | KMT2AMAPTNPC1HTTSIGMAR1 | |
| SCHEMBL27955199 | 0.71 | CYP19A1 (0.46) | CYP19A1MAPTKDM4ENPC1CTNNB1 | |
| Phenyl Phenylmethanesulfonate SCHEMBL27917341 | 0.71 | KMT2A (0.96) | KMT2AHTTFAAHCA1CA2 | |
| SCHEMBL25217311 | 0.71 | ALDH1A1 (0.48) | KMT2ACYP19A1MAPTHTTKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1015055-B | PROCESS FOR PREPARATION OF INDOLE DERIVATIVE AND ITS MODICAL USE | GLAXO GROUP LTD (GB) | 1991-12-11 | — | — | CN | disclosed |