Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27955193 | 0.78 | LMNA (0.51) | CYP19A1KDM4EMAPTHDAC1HDAC8 | |
| SCHEMBL29809566 | 0.78 | LMNA (0.51) | CYP19A1KDM4EMAPTHDAC1HDAC8 | |
| SCHEMBL1650589 | 0.76 | CA1 (0.51) | CYP19A1KDM4EMAPTHDAC1HDAC8 | |
| SCHEMBL30155019 | 0.76 | CA1 (0.51) | CYP19A1KDM4EMAPTHDAC1HDAC8 | |
| SCHEMBL8990514 | 0.76 | EPHX2 (0.53) | CYP19A1KDM4EMAPTHDAC1HDAC8 | |
| SCHEMBL9275073 | 0.75 | CYP19A1 (0.47) | CYP19A1KDM4EMAPTHDAC1HDAC8 | |
| Sulfuric Acid SCHEMBL1491064 | 0.73 | CA1 (0.48) | CYP19A1KDM4EMAPTHDAC1HDAC8 | |
| SCHEMBL5918472 | 0.73 | CYP19A1 (0.55) | CYP19A1KDM4EMAPTHDAC1HDAC8 | |
| SCHEMBL27290849 | 0.71 | KMT2A (0.55) | CYP19A1KDM4EMAPTHDAC1HDAC8 | |
| SCHEMBL6963327 | 0.70 | AHR (0.50) | CYP19A1KDM4EMAPTHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103724252-A | Preparation method of almotriptan | STONE LAKE PHARMA TECH CO LTD | 2014-04-16 | — | — | CN | disclosed |