Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 14/20 | 0.52 |
| ▸ | F13A1 | P00488 | 11/20 | 0.52 |
| ▸ | TGM1 | P22735 | 8/20 | 0.52 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102704 | 0.81 | NR1H2 (0.50) | TGM2F13A1TGM1TGM3USP2 | |
| SCHEMBL56379 | 0.80 | USP2 (0.53) | TGM2F13A1TGM1USP2SMN1; SMN2 | |
| SCHEMBL1487081 | 0.80 | USP2 (0.53) | TGM2F13A1TGM1TGM3USP2 | |
| SCHEMBL7406478 | 0.80 | USP2 (0.53) | TGM2F13A1TGM1TGM3USP2 | |
| SCHEMBL698803 | 0.78 | USP2 (0.69) | USP2SMN1; SMN2 | |
| SCHEMBL18294 | 0.78 | USP2 (0.69) | USP2SMN1; SMN2 | |
| SCHEMBL2249760 | 0.78 | USP2 (0.51) | TGM2F13A1TGM1USP2SMN1; SMN2 | |
| SCHEMBL3356491 | 0.78 | USP2 (0.55) | TGM2F13A1TGM1TGM3USP2 | |
| SCHEMBL20645184 | 0.77 | TGM2 (0.48) | TGM2F13A1TGM1TGM3USP2 | |
| SCHEMBL18914398 | 0.76 | USP2 (0.53) | TGM2F13A1TGM1USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132278-A1 | SYNTHESIS, PHARMACOLOGY AND USE OF NEW WATER-SOLUBLE AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS | UNIVERSITÄT REGENSBURG (DE) | 2024-06-27 | — | — | WO | disclosed |
| EP-4389223-A1 | SYNTHESIS, PHARMACOLOGY AND USE OF NEW WATER-SOLUBLE AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS | Universität Regensburg (DE) | 2024-06-26 | — | — | EP | disclosed |
| EP-4389223-A1 | SYNTHESIS, PHARMACOLOGY AND USE OF NEW WATER-SOLUBLE AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS | Universität Regensburg (DE) | 2024-06-26 | — | — | EP | disclosed |