Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3231208 | 0.89 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2ALOX12GAAMEN1 | |
| Methane SCHEMBL11380092 | 0.87 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2ALOX12GAAMEN1 | |
| SCHEMBL28980936 | 0.83 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2ALOX12GAAMEN1 | |
| SCHEMBL2223592 | 0.82 | KDM4E (0.61) | ALDH1A1GAAKMT2AMAPTKDM4E | |
| SCHEMBL28283953 | 0.81 | KMT2A (0.74) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL23014298 | 0.81 | RAB9A (0.61) | ALDH1A1SMN1; SMN2ALOX12GAAMEN1 | |
| SCHEMBL28483353 | 0.79 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2ALOX12GAAMEN1 | |
| SCHEMBL23014282 | 0.79 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2ALOX12GAAMEN1 | |
| SCHEMBL10988622 | 0.79 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2ALOX12GAAMEN1 | |
| SCHEMBL23014479 | 0.79 | KMT2A (0.73) | ALDH1A1SMN1; SMN2ALOX12GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1038103-A | The glutaramide diuretic agents of cycloalkyl substituted and its preparation method | PFIZER (US) | 1989-12-20 | — | — | CN | disclosed |