Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | RGS12 | O14924 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25319385 | 0.86 | DRD4 (0.46) | DRD4MMP12KMT2AMEN1RGS12 | |
| SCHEMBL27107109 | 0.82 | DRD4 (0.48) | DRD4PIK3CAMAPK13CSNK1DCSNK1E | |
| SCHEMBL30703395 | 0.70 | DRD4 (0.47) | DRD4MMP12KMT2AALDH1A1MEN1 | |
| SCHEMBL25897379 | 0.70 | DRD4 (0.47) | DRD4MMP12KMT2AALDH1A1MEN1 | |
| SCHEMBL2708013 | 0.70 | DRD4 (0.87) | DRD4KCNH2MMP12KMT2APOLB | |
| SCHEMBL25897359 | 0.69 | DRD4 (0.33) | DRD4KMT2AMEN1RGS12USP2 | |
| SCHEMBL29766557 | 0.69 | DRD4 (0.46) | DRD4MAPK14MMP12 | |
| SCHEMBL25316878 | 0.69 | DRD4 (0.46) | DRD4MAPK14MMP12 | |
| SCHEMBL29766565 | 0.69 | LMNA (0.32) | LMNAMAPT | |
| SCHEMBL569841 | 0.69 | PARP1 (0.56) | PIK3CAKCNH2PARP1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107658-A2 | INHIBITORS OF TYK2 | VYRNWY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |