SCHEMBL569841

SCHEMBL569841

Nc1cccc2c1OCC2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.56
LMNA P02545 2/20 0.41
MAPT P10636 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
CD44 P16070 1/20 0.37
DAO P14920 1/20 0.37
SLC6A2 P23975 3/20 0.35
SLC6A4 P31645 3/20 0.35
KCNH2 Q12809 1/20 0.35
PIK3CA P42336 2/20 0.35
AKT1 P31749 1/20 0.35
MTOR P42345 1/20 0.35
HTR6 P50406 1/20 0.34
CYP3A4 P08684 2/20 0.33
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL25315101 0.98 PARP1 (0.55) PARP1LMNAMAPTALDH1A1HPGD
Hydrochloric Acid SCHEMBL31009377 0.98 PARP1 (0.55) PARP1LMNAMAPTALDH1A1HPGD
SCHEMBL6584391 0.88 PARP1 (0.44) PARP1LMNAMAPTALDH1A1HPGD
SCHEMBL29509042 0.88 PARP1 (0.44) PARP1LMNAMAPTALDH1A1HPGD
Hydrochloric Acid SCHEMBL30378456 0.86 PARP1 (0.43) PARP1LMNAMAPTALDH1A1HPGD
SCHEMBL2061156 0.86 PARP1 (0.43) PARP1LMNAMAPTALDH1A1HPGD
SCHEMBL30051454 0.79 PARP1 (0.41) PARP1LMNAMAPTDAODYRK1A
SCHEMBL19582237 0.75 CD44 (0.51) CD44
SCHEMBL13635655 0.74 PARP1 (0.52) PARP1SLC6A2SLC6A4KCNH2HRH1
SCHEMBL2007697 0.74 PARP1 (0.52) PARP1SLC6A2SLC6A4KCNH2HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12448360-B2 Synthesis method for preparing SGLT inhibitor intermediate DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2025-10-21 US claimed
EP-4212520-B1 SYNTHESIS METHOD FOR PREPARING SGLT INHIBITOR INTERMEDIATES DAEWOONG PHARMACEUTICAL CO LTD (KR) 2025-08-13 EP claimed
US-20230322699-A1 SYNTHESIS METHOD FOR PREPARING SGLT INHIBITOR INTERMEDIATE DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2023-10-12 US claimed
CN-112094253-B Synthetic method for preparing SGLT inhibitor intermediate 株式会社大熊制药 2023-01-10 CN claimed
US-4647677-A Process for preparing 2,3-dihydro-7-aminobenzofurans MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1987-03-03 US claimed
JP-7126881-A None JP disclosed
EP-4695244-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
US-12448360-B2 Synthesis method for preparing SGLT inhibitor intermediate DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2025-10-21 US disclosed
US-12448360-B2 Synthesis method for preparing SGLT inhibitor intermediate DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2025-10-21 US disclosed
US-12391663-B2 Isoindolinone compounds MONTE ROSA THERAPEUTICS AG (CH) 2025-08-19 US disclosed
EP-4212520-B1 SYNTHESIS METHOD FOR PREPARING SGLT INHIBITOR INTERMEDIATES DAEWOONG PHARMACEUTICAL CO LTD (KR) 2025-08-13 EP disclosed
US-12358879-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-07-15 US disclosed
US-4647677-A Process for preparing 2,3-dihydro-7-aminobenzofurans MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1987-03-03 US disclosed
US-4514211-A HERBICIDES, PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-04-30 US disclosed
EP-0138280-A2 Blood-pressure lowering piperazine derivatives DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1985-04-24 EP disclosed
EP-0048040-B1 7-SUBSTITUTED 2,3-DIHYDROBENZOFURANS, THEIR PREPARATION AND THEIR USE AS PESTICIDES OR AS CHEMICAL INTERMEDIATES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1984-08-29 EP disclosed
EP-0079683-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-05-25 EP disclosed
EP-0048040-A1 7-Substituted 2,3-dihydrobenzofurans, their preparation and their use as pesticides or as chemical intermediates SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1982-03-24 EP disclosed
US-4302592-A Pesticidal 3-(2,3-dihydrobenzofuran-7-yl)-5-methoxy-1,3,4-oxadiazol-2(3H)-one SHELL OIL COMPANY (US) 1981-11-24 US disclosed
US-3963717-A ANTIINFLAMMATORY, ANALGESIC SANDOZ, INC. (US) 1976-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12448360-B2 Synthesis method for preparing SGLT inhibitor intermediate SLC5A2, SLC5A1, SLC2A1 PARP1 3375/4885LMNA 4377/4885MAPT 429/4885
US-12391663-B2 Isoindolinone compounds CYP4F2, AOC2, AOC3 PARP1 4554/4885LMNA 1164/4885MAPT 4795/4885
US-12358879-B2 Heterocyclic compound PARK7, SMN1; SMN2, SNCA PARP1 1873/4885LMNA 420/4885MAPT 44/4885
US-20230322699-A1 SYNTHESIS METHOD FOR PREPARING SGLT INHIBITOR INTERMEDIATE SLC5A2, SLC5A1, SLC2A1 PARP1 3375/4885LMNA 4377/4885MAPT 429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.