Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12447398 | 0.83 | F10 (0.50) | SMN1; SMN2MAPTRAB9ALMNANPC1 | |
| SCHEMBL1243901 | 0.80 | CYP4F2 (0.46) | SMN1; SMN2MAPTRAB9ALMNANPC1 | |
| SCHEMBL13301843 | 0.78 | HSD17B2 (0.50) | SMN1; SMN2MAPTRAB9ALMNANPC1 | |
| SCHEMBL16023430 | 0.77 | NPC1 (0.54) | SMN1; SMN2RAB9ANPC1CYP4F2CYP4A11 | |
| SCHEMBL1248647 | 0.77 | SMN1; SMN2 (0.65) | SMN1; SMN2MAPTRAB9ALMNANPC1 | |
| SCHEMBL1989713 | 0.77 | KMT2A (0.62) | SMN1; SMN2MAPTRAB9ALMNANPC1 | |
| SCHEMBL8699083 | 0.77 | CYP4F2 (0.46) | SMN1; SMN2MAPTRAB9ALMNANPC1 | |
| SCHEMBL14147865 | 0.77 | HSD17B2 (0.49) | SMN1; SMN2MAPTRAB9ALMNANPC1 | |
| SCHEMBL110276 | 0.77 | CYP4F2 (0.65) | SMN1; SMN2RAB9ALMNANPC1ALDH1A1 | |
| SCHEMBL16011467 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTRAB9ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2360161-B1 | Preparation and use of magnesium amides | MUNICHEM GMBH (DE) | 2016-08-31 | — | — | EP | disclosed |
| EP-2360161-B1 | Preparation and use of magnesium amides | MUNICHEM GMBH (DE) | 2016-08-31 | — | — | EP | disclosed |
| US-8134005-B2 | Preparation and use of magnesium amides | Ludwig-Maximilians-Universitat München (DE) | 2012-03-13 | — | — | US | disclosed |
| US-8134005-B2 | Preparation and use of magnesium amides | Ludwig-Maximilians-Universitat München (DE) | 2012-03-13 | — | — | US | disclosed |
| EP-2360161-A1 | Preparation and use of magnesium amides | Ludwig-Maximilians-Universität München (DE) | 2011-08-24 | — | — | EP | disclosed |
| EP-2360161-A1 | Preparation and use of magnesium amides | Ludwig-Maximilians-Universität München (DE) | 2011-08-24 | — | — | EP | disclosed |
| EP-1981893-B1 | PREPARATION AND USE OF MAGNESIUM AMIDES | UNIV MUENCHEN L MAXIMILIANS (DE) | 2011-06-08 | — | — | EP | disclosed |
| EP-1981893-B1 | PREPARATION AND USE OF MAGNESIUM AMIDES | UNIV MUENCHEN L MAXIMILIANS (DE) | 2011-06-08 | — | — | EP | disclosed |
| US-20100144516-A1 | PREPARATION AND USE OF MAGNESIUM AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2010-06-10 | — | — | US | disclosed |
| US-20100144516-A1 | PREPARATION AND USE OF MAGNESIUM AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2010-06-10 | — | — | US | disclosed |
| EP-2142556-A1 | PREPARATION AND USE OF MAGNESIUM AMIDES | Ludwig-Maximilians-Universität München (DE) | 2010-01-13 | — | — | EP | disclosed |
| US-20090176988-A1 | Preparation and Use of Magnesium Amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUENCHEN (DE) | 2009-07-09 | — | — | US | disclosed |
| US-20090176988-A1 | Preparation and Use of Magnesium Amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUENCHEN (DE) | 2009-07-09 | — | — | US | disclosed |
| EP-1981893-A1 | PREPARATION AND USE OF MAGNESIUM AMIDES | Ludwig-Maximilians-Universität München (DE) | 2008-10-22 | — | — | EP | disclosed |
| WO-2008087057-A1 | PREPARATION AND USE OF MAGNESIUM AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008087057-A1 | PREPARATION AND USE OF MAGNESIUM AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) | 2008-07-24 | — | — | WO | disclosed |
| WO-2007082911-A1 | PREPARATION AND USE OF MAGNESIUM AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007082911-A1 | PREPARATION AND USE OF MAGNESIUM AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176988-A1 | Preparation and Use of Magnesium Amides | MLX, GLRX3, SFXN3 | SMN1; SMN2 2395/4885MAPT 4467/4885RAB9A 3507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.