Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.49 |
| ▸ | CTSK | P43235 | 6/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675710 | 0.90 | CTSS (0.53) | CTSSCTSKKLK5CTSBCTSL | |
| SCHEMBL10143850 | 0.90 | CTSS (0.53) | CTSSCTSKKLK5CTSBCTSL | |
| SCHEMBL31321421 | 0.90 | CTSS (0.53) | CTSSCTSKKLK5CTSBCTSL | |
| SCHEMBL3316394 | 0.88 | KLK5 (0.60) | CTSSCTSKKLK5CTSBCTSL | |
| SCHEMBL3498608 | 0.88 | KLK5 (0.60) | CTSSCTSKKLK5CTSBCTSL | |
| SCHEMBL19212612 | 0.88 | KLK5 (0.60) | CTSSCTSKKLK5CTSBCTSL | |
| Acetic Acid SCHEMBL2728774 | 0.88 | KLK5 (0.59) | CTSSCTSKKLK5CTSBCTSL | |
| SCHEMBL30532488 | 0.87 | CTSS (0.62) | CTSSCTSKKLK5CTSBCTSL | |
| SCHEMBL13913373 | 0.86 | CTSS (0.50) | CTSSCTSKKLK5CTSBCTSL | |
| SCHEMBL1620166 | 0.86 | CTSS (0.50) | CTSSCTSKKLK5CTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012058325-A1 | COMPOUNDS AND METHODS USEFUL FOR TREATMENT OF DISEASES MEDIATED BY HIF-1 | ONCOTHYREON INC. (US) | 2012-05-03 | — | — | WO | disclosed |