Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.50 |
| ▸ | CTSK | P43235 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PPID | Q08752 | 2/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13913373 | 1.00 | CTSS (0.50) | CTSSCTSKCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2982541 | 1.00 | CTSS (0.50) | CTSSCTSKCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31321421 | 0.91 | CTSS (0.53) | CTSSCTSKMAPTKLK5CTSL | |
| SCHEMBL6675710 | 0.91 | CTSS (0.53) | CTSSCTSKMAPTKLK5CTSL | |
| SCHEMBL10143850 | 0.91 | CTSS (0.53) | CTSSCTSKMAPTKLK5CTSL | |
| SCHEMBL18239927 | 0.90 | CTSS (0.60) | CTSSCTSKALDH1A1MAPTKLK5 | |
| SCHEMBL3498608 | 0.90 | KLK5 (0.60) | CTSSCTSKKLK5CTSLCTSB | |
| SCHEMBL14803767 | 0.90 | PPARG (0.53) | CTSSCTSKCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20045974 | 0.90 | PPARG (0.53) | CTSSCTSKCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19212612 | 0.90 | KLK5 (0.60) | CTSSCTSKKLK5CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7928236-B2 | Fluorescent amino acid derivatives | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2011-04-19 | — | — | US | claimed |
| US-20100152417-A1 | Fluorescent Amino Acid Derivatives | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2010-06-17 | — | — | US | claimed |
| US-7928236-B2 | Fluorescent amino acid derivatives | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2011-04-19 | — | — | US | disclosed |
| US-7928236-B2 | Fluorescent amino acid derivatives | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2011-04-19 | — | — | US | disclosed |
| US-7928236-B2 | Fluorescent amino acid derivatives | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2011-04-19 | — | — | US | disclosed |
| US-7786177-B2 | Phenylalanine enamide derivatives | UCB PHARMA S.A. (BE) | 2010-08-31 | — | — | US | disclosed |
| US-20100152417-A1 | Fluorescent Amino Acid Derivatives | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100152417-A1 | Fluorescent Amino Acid Derivatives | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100152417-A1 | Fluorescent Amino Acid Derivatives | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2010-06-17 | — | — | US | disclosed |
| US-7645770-B2 | Phenylalanine enamide derivatives | UCB PHARMA S.A. (BE) | 2010-01-12 | — | — | US | disclosed |
| US-20090186914-A1 | Phenylalanine Enamide Derivatives | UCB PHARMA, S.A. (BE) | 2009-07-23 | — | — | US | disclosed |
| WO-2002068393-A1 | PHENYLALANINE ENAMIDE DERIVATIVES POSSESSING A CYCLOBUTENE GROUP, FOR USE AS INTEGRIN INHIBITORS | CELLTECH R & D LIMITED (GB) | 2002-09-06 | — | — | WO | disclosed |
| US-20020115684-A1 | 2, 7-naphthyridine derivatives | CELLTECH R&D, LTD. (GB) | 2002-08-22 | — | — | US | disclosed |
| US-20020037909-A1 | Enamine derivatives | UCB PHARMA S.A. (BE) | 2002-03-28 | — | — | US | disclosed |
| US-20020028812-A1 | Phenylalanine derivatives | CELLTECH CHIROSCIENCE LIMITED (GB) | 2002-03-07 | — | — | US | disclosed |
| EP-1181266-A1 | SQUARIC ACID DERIVATIVES AS CELL ADHESION MOLECULES | Celltech R&D Limited (GB) | 2002-02-27 | — | — | EP | disclosed |
| WO-2001079173-A2 | ENAMINE DERIVATIVES AS CELL ADHESION MOLECULES | CELLTECH R & D LIMITED (GB) | 2001-10-25 | — | — | WO | disclosed |
| EP-1117657-A1 | PHENYLALANINE DERIVATIVES AS ALPHA 4 INTEGRIN INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000073260-A1 | SQUARIC ACID DERIVATIVES AS CELL ADHESION MOLECULES | CELLTECH R&D LIMITED (GB) | 2000-12-07 | — | — | WO | disclosed |
| WO-2000018759-A1 | PHENYLALANINE DERIVATIVES AS ALPHA 4 INTEGRIN INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 2000-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028812-A1 | Phenylalanine derivatives | PAH, FPR1, VCAM1 | CTSS 3430/4885CTSK 4202/4885CYP1A2 588/4885 |
| US-20020037909-A1 | Enamine derivatives | CCR1, ITGB2, CCR10 | CTSS 2409/4885CTSK 1977/4885CYP1A2 521/4885 |
| US-20100152417-A1 | Fluorescent Amino Acid Derivatives | BCAT1, BCAT2, DNPEP | CTSS 2754/4885CTSK 2856/4885CYP1A2 4203/4885 |
| US-20020115684-A1 | 2, 7-naphthyridine derivatives | VCAM1, ICAM1, SELL | CTSS 1875/4885CTSK 2831/4885CYP1A2 1658/4885 |
| US-20090186914-A1 | Phenylalanine Enamide Derivatives | PAH, HRH3, PRLHR | CTSS 1681/4885CTSK 1532/4885CYP1A2 811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.