SCHEMBL27296308

SCHEMBL27296308

CCOC(=O)C(O)SCC

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
LMNA P02545 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ALOX15 P16050 2/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SOAT1 P35610 1/20 0.39
HCAR2 Q8TDS4 1/20 0.37
METAP2 P50579 4/20 0.37
METAP1 P53582 2/20 0.37
TRPA1 O75762 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP2D6 P10635 1/20 0.33
PIN1 Q13526 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27857882 0.82 HCAR2 (0.41) ALDH1A1LMNAHSD17B10HCAR2TSHR
SCHEMBL109870 0.80 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL27630386 0.79 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL27631256 0.78
SCHEMBL11493884 0.78 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL27625286 0.77 TSHR (0.41) ALDH1A1LMNAHSD17B10CYP3A4TSHR
SCHEMBL9775068 0.76 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL21802633 0.76 EPHX1 (0.49) LMNAHSD17B10
SCHEMBL11671511 0.74 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL9673439 0.73 GAA (0.43) ALDH1A1LMNAHSD17B10ALOX15MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110327665-A Multi-functional defoaming agent of aqueous, environmental protective nanometer copolymer and preparation method thereof 江苏广成化工有限公司 2019-10-15 CN claimed
CN-109354688-A Environment-friendly water-based block copolymer dispersant and preparation method thereof 江苏广成化工有限公司 2019-02-19 CN claimed
CN-102827135-A Compound for preparing medicine for treating avian influenza and preparation method of compound UNIV GUANGDONG PHARM 2012-12-19 CN claimed
CN-110385086-A Aqueous, environmental protective multifunctional nano block wetting agent and preparation method thereof 江苏广成化工有限公司 2019-10-29 CN disclosed
CN-110327665-A Multi-functional defoaming agent of aqueous, environmental protective nanometer copolymer and preparation method thereof 江苏广成化工有限公司 2019-10-15 CN disclosed
CN-109568166-A Fragrance material 宝洁公司 2019-04-05 CN disclosed
CN-109354688-A Environment-friendly water-based block copolymer dispersant and preparation method thereof 江苏广成化工有限公司 2019-02-19 CN disclosed
CN-101111497-B Fused thiophenes, process for their preparation and their use CORNING INC 2013-10-30 CN disclosed
CN-102827135-A Compound for preparing medicine for treating avian influenza and preparation method of compound UNIV GUANGDONG PHARM 2012-12-19 CN disclosed
CN-101668762-A Fused thiophenes, methods for making fused thiophenes, and uses thereof CORNING INC 2010-03-10 CN disclosed
CN-100540534-C N-alkynyl-2-(aryloxy of replacement) alkylthioamide derivatives as mycocide SYNGENTA LTD (GB) 2009-09-16 CN disclosed
CN-101111497-A Fused thiophenes, process for their preparation and their use CORNING INC (US) 2008-01-23 CN disclosed
CN-1812966-A N-alkynyl-2- (substituted aryloxy) alkylthioamide derivatives as fungicides SYNGENTA LTD (GB) 2006-08-02 CN disclosed
CN-1384832-A Pesticidal aminoheterocyclamide compounds NOVARTIS AG (CH) 2002-12-11 CN disclosed
CN-1384826-A Pesticidal N-heteroaryl alpha-alkoximino-carboxamides NOVARITS AG (CH) 2002-12-11 CN disclosed
CN-1036006-C Antibiotic compounds ZENECA LTD (GB) 1997-10-01 CN disclosed
CN-1079224-A Antifungal compound ZENECA LTD (GB) 1993-12-08 CN disclosed