Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27631256 | 0.82 | — | — | |
| SCHEMBL27296308 | 0.80 | ALDH1A1 (0.42) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL111432 | 0.80 | HCAR2 (0.39) | ALDH1A1HSD17B10LMNAL3MBTL1CYP3A4 | |
| Hydrochloric Acid SCHEMBL28966621 | 0.78 | — | — | |
| SCHEMBL109355 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNAL3MBTL1TDP1TSHR | |
| Hydrochloric Acid SCHEMBL3333430 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL2655388 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL275716 | 0.76 | ALOX15 (0.50) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL903490 | 0.75 | — | — | |
| SCHEMBL805601 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HSD17B10LMNAALOX15MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102802605-A | Stable lipid formulations of apoptosis promoters | ABBOTT LAB | 2012-11-28 | — | — | CN | claimed |
| EP-2424499-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | Abbott Laboratories (US) | 2012-03-07 | — | — | EP | claimed |
| WO-2010127193-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | ABBOTT LABORATORIES (US) | 2010-11-04 | — | — | WO | claimed |
| US-20100278905-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | ABBVIE INC. | 2010-11-04 | — | — | US | claimed |
| US-4122258-A | Process for producing desacetoxycephalosporin derivatives by heating a penicillin-1-oxide in presence of an organic sulfide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-10-24 | — | — | US | claimed |
| US-20220326613-A1 | PHOTOSENSITIVE TRANSFER MATERIAL AND METHOD OF PRODUCING THE SAME, METHOD OF PRODUCING PATTERNED METAL CONDUCTIVE MATERIAL, FILM, TOUCH PANEL, METHOD OF SUPPRESSING DETERIORATION, AND LAMINATE | FUJIFILM CORPORATION (JP) | 2022-10-13 | — | — | US | disclosed |
| US-10838111-B2 | Optical material comprising a red-shifted benzotriazole UV absorber | ESSILOR INTERNATIONAL (FR) | 2020-11-17 | — | — | US | disclosed |
| EP-3161528-B1 | COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN UV-ABSORBER AND AN ANTI-YELLOWING ADDITIVE | ESSILOR INT (FR) | 2020-03-04 | — | — | EP | disclosed |
| US-10370520-B2 | Composition for the manufacture of an ophthalmic lens comprising an UV-absorber and an anti-yellowing additive | ESSILOR INTERNATIONAL (FR) | 2019-08-06 | — | — | US | disclosed |
| US-20190107647-A1 | OPTICAL MATERIAL COMPRISING A RED-SHIFTED BENZOTRIAZOLE UV ABSORBER | ESSILOR INTERNATIONAL (FR) | 2019-04-11 | — | — | US | disclosed |
| EP-3236296-A1 | OPTICAL MATERIAL COMPRISING A RED-SHIFTED BENZOTRIAZOLE UV ABSORBER | ESSILOR INTERNATIONAL (Compagnie Générale d'Optique) (FR) | 2017-10-25 | — | — | EP | disclosed |
| US-20170121498-A1 | Composition for the Manufacture of an Ophthalmic Lens Comprising an UV-Absorber and an Anti-Yellowing Additive | ESSILOR INTERNATIONAL (FR) | 2017-05-04 | — | — | US | disclosed |
| US-20020058691-A1 | 3,4-Diaryl Thiophenes and analogs thereof having use as antiflammatory agents | TALLEY JOHN J (US) | 2002-05-16 | — | — | US | disclosed |
| US-6383561-B1 | TONER PARTICLES PREPARED BY EMULSION AGGREGATION FORM PROPELLANT STREAM; INK JET PRINTING | XEROX CORPORATION | 2002-05-07 | — | — | US | disclosed |
| US-6365318-B1 | OXIDATIVE POLYMERIZATION OF PYRROLE OR THIOPHENE MONOMERS IN DISPERSION WITH TONER PARTICLES; SUBSEQUENT CHARGING TO NEGATIVE OR POSITIVE POLARITY | XEROX CORPORATION | 2002-04-02 | — | — | US | disclosed |
| US-6274590-B1 | ADMINISTERING 3,4-DIARYLTHIOPHENE DERIVATIVE TO TREAT ECZEMA, BURNS, PSORIASIS, AND DERMATITIS | G. D. SEARLE & CO. | 2001-08-14 | — | — | US | disclosed |
| EP-0679157-B1 | NOVEL 3,4-DIARYL THIOPHENES AND ANALOGS THEREOF HAVING USE AS ANTIINFLAMMATORY AGENTS | SEARLE & CO (US) | 1997-11-19 | — | — | EP | disclosed |
| EP-0679157-A1 | NOVEL 3,4-DIARYL THIOPHENES AND ANALOGS THEREOF HAVING USE AS ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1995-11-02 | — | — | EP | disclosed |
| WO-1994015932-A1 | NOVEL 3,4-DIARYL THIOPHENES AND ANALOGS THEREOF HAVING USE AS ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1994-07-21 | — | — | WO | disclosed |
| US-4122258-A | Process for producing desacetoxycephalosporin derivatives by heating a penicillin-1-oxide in presence of an organic sulfide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058691-A1 | 3,4-Diaryl Thiophenes and analogs thereof having use as antiflammatory agents | NR3C1, FPR1, NR4A1 | ALDH1A1 240/4885HSD17B10 975/4885LMNA 3474/4885 |
| US-20190107647-A1 | OPTICAL MATERIAL COMPRISING A RED-SHIFTED BENZOTRIAZOLE UV ABSORBER | CRY2, ALDH1A2, CRY1 | ALDH1A1 201/4885HSD17B10 2065/4885LMNA 1417/4885 |
| US-10838111-B2 | Optical material comprising a red-shifted benzotriazole UV absorber | CRY2, ALDH1A2, CRY1 | ALDH1A1 201/4885HSD17B10 2065/4885LMNA 1417/4885 |
| US-20100278905-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | BCL2, BAX, BCOR | ALDH1A1 3985/4885HSD17B10 481/4885LMNA 2007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.