Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.57 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.56 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13612743 | 0.94 | DRD2 (0.69) | DRD2SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL256656 | 0.84 | DRD2 (0.78) | DRD2SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL5888867 | 0.84 | HRH3 (0.68) | SIGMAR1MEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL27571644 | 0.83 | DRD2 (0.76) | DRD2SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL15779804 | 0.83 | DRD2 (0.76) | DRD2SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL152587 | 0.83 | DRD2 (0.81) | DRD2SIGMAR1MEN1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL7259165 | 0.81 | SIGMAR1 (0.75) | DRD2SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL3399715 | 0.79 | DRD2 (1.00) | DRD2SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL5888791 | 0.79 | HRH3 (0.74) | DRD2SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL2097765 | 0.78 | SIGMAR1 (0.69) | DRD2SIGMAR1MEN1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1037841-C | Process for preparing substituted 4-phenyl-4-piperidinecarboxamide having local anaesthetic and analgesic effect | ASTRA CO (SE) | 1998-03-25 | — | — | CN | disclosed |
| CN-1053605-A | Preparation method with new replacement 4-phenyl-4-piperidyl urea of toponarcosis and analgesic effect | ASTRA AB (SE) | 1991-08-07 | — | — | CN | disclosed |