Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10581522 | 0.87 | ALDH1A1 (0.75) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL9938816 | 0.86 | MAOB (0.50) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL9938980 | 0.80 | KMT2A (0.56) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL1035480 | 0.79 | ALDH1A1 (0.66) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL27922018 | 0.79 | ALDH1A1 (0.63) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL9938380 | 0.79 | MRGPRX4 (0.68) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL2388510 | 0.78 | GAA (0.60) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| Hydrochloric Acid SCHEMBL7729822 | 0.78 | ALDH1A1 (0.64) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL2387646 | 0.78 | ALDH1A1 (0.64) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL23673927 | 0.76 | GAA (0.62) | KDM4EALDH1A1HSD17B10HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035939-C | Substituted (arylalkylaminobenzyl) aminopropionamide derivatives, their preparation and use anti-eptic, neuroprotective and antidepressant agents | ERBA FARMITALIA (IT) | 1997-09-24 | — | — | CN | disclosed |
| CN-1104018-A | Substituted (aralkylaminobenzyl) aminopropionamide derivatives and process for their preparation | ERBA FARMITALIA (IT) | 1995-06-21 | — | — | CN | disclosed |