Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.66 |
| ▸ | GAA | P10253 | 5/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | GLA | P06280 | 2/20 | 0.66 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | CASP7 | P55210 | 1/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | ABL1 | P00519 | 1/20 | 0.64 |
| ▸ | CFTR | P13569 | 3/20 | 0.63 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7729822 | 0.98 | ALDH1A1 (0.64) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL21857075 | 0.86 | ALDH1A1 (0.58) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL165608 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL23540246 | 0.83 | KDM4E (0.51) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL29654804 | 0.83 | KDM4E (0.51) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL3726926 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL30301996 | 0.82 | SLC6A4 (0.51) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL2708451 | 0.82 | SLC6A4 (0.51) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL1559630 | 0.82 | HDAC1 (0.46) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL16353322 | 0.82 | KDM4E (0.83) | ALDH1A1KDM4EGAAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351946-A2 | MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT | ICOS CORPORATION (US) | 2003-10-15 | — | — | EP | claimed |
| US-20020165218-A1 | Materials and methods to potentiate cancer treatment | LUITPOLD PHARMACEUTICALS, INC. | 2002-11-07 | — | — | US | claimed |
| WO-2002020500-A2 | MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT | ICOS CORPORATION (US) | 2002-03-14 | — | — | WO | claimed |
| US-12606522-B2 | Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives | ORSOBIO, INC. (US) | 2026-04-21 | — | — | US | disclosed |
| US-20250213575-A1 | 8-HETEROCYCLIC-3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES AS ANTI-BACTERIALS | BioVersys AG (CH) | 2025-07-03 | — | — | US | disclosed |
| WO-2025136936-A1 | AGONISTS OF TREM2 ACTIVITY | MERCK SHARP & DOHME LLC (US) | 2025-06-26 | — | — | WO | disclosed |
| US-20250197413-A1 | RXFP1 RECEPTOR AGONISTS | ELI LILLY AND COMPANY | 2025-06-19 | — | — | US | disclosed |
| WO-2025128938-A1 | BENZOTHIAZOLE DERIVATIVES USEFUL AS RXFP1 RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2025-06-19 | — | — | WO | disclosed |
| CN-120117999-A | Fluorotranilast derivatives and medical application thereof | 中国药科大学 | 2025-06-10 | — | — | CN | disclosed |
| CN-119143671-B | Method for simply and conveniently synthesizing quinolinone derivative through one-pot method of carboinsertion reaction | 九洲药业(杭州)有限公司 | 2025-05-16 | — | — | CN | disclosed |
| EP-4543884-A1 | 8-HETEROCYCLIC-3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES AS ANTI-BACTERIALS | BioVersys AG (CH) | 2025-04-30 | — | — | EP | disclosed |
| US-5739133-A | N-ACYLATED AND ALKYLATED DERIVATIVES OF PYRIDAZINO(4,5-B)-QUINOLINES; EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS; STROKES; ANTIISCHEMIC AND HYPOGLYCEMIC AGENTS; PSYCHOSIS; NEUROGODEGENERATIVE DISORDERS | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | disclosed |
| US-5733910-A | Pyridazinedione compounds useful in the treating neurological disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1998-03-31 | — | — | US | disclosed |
| US-5604227-A | EXCITATORY AMINO ACID ANTAGONIST; MONO, DI OR TRI-ACETYLATION OR ALKYLATION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1997-02-18 | — | — | US | disclosed |
| US-5599814-A | SUBSTITUTED PYRIDAZINO(4,5-B)QUINOLINES AS ANTAGONISTS OF EXCITATORY AMINO ACIDS | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1997-02-04 | — | — | US | disclosed |
| EP-0516297-B1 | Pyridazinediones and their use in the treatment of neurological disorders | ZENECA LTD (GB) | 1996-10-30 | — | — | EP | disclosed |
| EP-0516297-A1 | Pyridazinediones and their use in the treatment of neurological disorders | ZENECA LIMITED (GB) | 1992-12-02 | — | — | EP | disclosed |
| US-5093364-A | 5-FLUOROANTHRANILIC FUNGICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-03-03 | — | — | US | disclosed |
| EP-0360417-A2 | Derivatives of 4-fluoroanthranilic acid and their use as fungicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1990-03-28 | — | — | EP | disclosed |
| US-4198350-A | Amination/demethylation process | STANDARD OIL COMPANY (INDIANA) (US) | 1980-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250197413-A1 | RXFP1 RECEPTOR AGONISTS | RXFP1, RXFP3, RXFP2 | ALDH1A1 1973/4885KDM4E 3828/4885GAA 3322/4885 |
| US-20250213575-A1 | 8-HETEROCYCLIC-3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES AS ANTI-BACTERIALS | CUTA, AP1S1, SUB1 | ALDH1A1 3861/4885KDM4E 1939/4885GAA 3404/4885 |
| US-12606522-B2 | Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives | NR3C2, NR5A1, SRD5A2 | ALDH1A1 1507/4885KDM4E 3921/4885GAA 2559/4885 |
| US-20020165218-A1 | Materials and methods to potentiate cancer treatment | DCK, CHEK2, CHEK1 | ALDH1A1 3519/4885KDM4E 2518/4885GAA 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.