Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GPR39 | O43194 | 2/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | FABP1 | P07148 | 1/20 | 0.45 |
| ▸ | FABP6 | P51161 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18947190 | 0.82 | NPSR1 (0.66) | GAAPOLBL3MBTL1NPSR1KDM4E | |
| SCHEMBL29580189 | 0.81 | POLB (0.69) | GAAPOLBL3MBTL1NPSR1KDM4E | |
| SCHEMBL29579757 | 0.79 | GAA (0.57) | GAAPOLBL3MBTL1NPSR1KDM4E | |
| SCHEMBL29579775 | 0.78 | ALDH1A1 (0.65) | GAAPOLBL3MBTL1NPSR1KDM4E | |
| SCHEMBL14321086 | 0.76 | GAA (0.53) | GAAPOLBL3MBTL1NPSR1KDM4E | |
| SCHEMBL14321655 | 0.76 | GAA (0.53) | GAAPOLBL3MBTL1NPSR1KDM4E | |
| SCHEMBL22994911 | 0.75 | CYP1A2 (0.49) | KDM4EALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL29579974 | 0.73 | POLB (0.74) | GAAPOLBL3MBTL1NPSR1KDM4E | |
| SCHEMBL14321211 | 0.72 | GAA (0.42) | GAAPOLBL3MBTL1NPSR1KDM4E | |
| SCHEMBL14321212 | 0.72 | GAA (0.42) | GAAPOLBL3MBTL1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026056-A2 | HETEROARYL COMPOUNDS AS EGFR INHIBITORS AND THEIR USES | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-02-01 | — | — | WO | disclosed |