SCHEMBL2729965

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2729397	0.87	FFAR4 (0.34)	PPARDPPARGPPARAFFAR4ALDH1A1
	SCHEMBL2729981	0.86	FFAR4 (0.33)	PPARDPPARGPPARAFFAR4ALDH1A1
	SCHEMBL2720240	0.85	PPARG (0.40)	PPARDPPARGPPARAMRGPRX4FFAR4
	SCHEMBL2829748	0.84	TP53 (0.37)	PPARGFFAR4ALDH1A1TP53MAPT
	SCHEMBL2731903	0.81	SLC5A2 (0.34)	ALDH1A1SLC5A2GLASLC5A1
	SCHEMBL2720790	0.81	ALDH1A1 (0.55)	PPARDPPARGPPARAMRGPRX4FFAR4
	SCHEMBL18935421	0.81	ALDH1A1 (0.55)	PPARDPPARGPPARAMRGPRX4FFAR4
	SCHEMBL2729773	0.80	SSTR4 (0.40)	MRGPRX4ALDH1A1SLC5A2GLASLC5A1
	SCHEMBL2729993	0.78	MCHR1 (0.32)	—
	SCHEMBL2729949	0.78	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.