Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.39 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27295072 | 1.00 | CYP2C9 (0.41) | CYP2C9CYP2C19LMNACYP1A2RECQL | |
| SCHEMBL27295071 | 1.00 | CYP2C9 (0.41) | CYP2C9CYP2C19LMNACYP1A2RECQL | |
| SCHEMBL4918201 | 0.84 | DRD4 (0.41) | CARM1PRMT6 | |
| SCHEMBL27389644 | 0.84 | DRD4 (0.41) | CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL4917162 | 0.83 | DRD4 (0.41) | CARM1PRMT6 | |
| SCHEMBL27365754 | 0.78 | TACR1 (0.53) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7837990 | 0.77 | TACR1 (0.52) | SMN1; SMN2 | |
| SCHEMBL7824569 | 0.76 | NR3C1 (0.38) | — | |
| SCHEMBL7824564 | 0.76 | NR3C1 (0.38) | — | |
| SCHEMBL7824572 | 0.76 | NR3C1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1045595-C | Process for the preparation of the intermediates used in the synthesis of 3-aminopiperidine derivatives | PFIZER (US) | 1999-10-13 | — | — | CN | disclosed |
| CN-1035944-C | 3-aminopiperidine derivatives and related nitrogen-containing heterocyclic compounds | PFIZER (US) | 1997-09-24 | — | — | CN | disclosed |
| CN-1087083-A | The intermediates preparation of synthetic 3-amino piperidine derivatives | PFIZER (US) | 1994-05-25 | — | — | CN | disclosed |
| CN-1053060-A | 3-aminopiperidine derivatives and related nitrogen-containing heterocycles | PFIZER (US) | 1991-07-17 | — | — | CN | disclosed |