Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4918201 | 1.00 | DRD4 (0.41) | DRD4DRD2DRD1DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL4917162 | 0.99 | DRD4 (0.41) | DRD4DRD2DRD1DRD5DRD3 | |
| SCHEMBL27295071 | 0.84 | CYP2C9 (0.41) | CARM1PRMT6 | |
| SCHEMBL27295072 | 0.84 | CYP2C9 (0.41) | CARM1PRMT6 | |
| SCHEMBL27300413 | 0.84 | CYP2C9 (0.41) | CARM1PRMT6 | |
| SCHEMBL4907101 | 0.82 | TACR1 (0.51) | SIGMAR1TACR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4919498 | 0.81 | TACR1 (0.50) | SIGMAR1TACR1MEN1KMT2A | |
| SCHEMBL4908044 | 0.81 | TACR1 (0.46) | DRD2TACR1HCRTR1HCRTR2SCN9A | |
| SCHEMBL4913542 | 0.80 | TACR1 (0.52) | SIGMAR1TACR1HCRTR1HCRTR2MEN1 | |
| SCHEMBL6700500 | 0.80 | TACR1 (0.52) | SIGMAR1TACR1HCRTR1HCRTR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1525858-A | A pharmaceutical composition comprising a nicotinic receptor partial antagonist and an antiemetic agent for modulating cholinergic function | �Ʒ� | 2004-09-01 | — | — | CN | claimed |
| CN-1525858-A | A pharmaceutical composition comprising a nicotinic receptor partial antagonist and an antiemetic agent for modulating cholinergic function | �Ʒ� | 2004-09-01 | — | — | CN | disclosed |
| CN-1056373-C | Process for preparing fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles | PFIZER (US) | 2000-09-13 | — | — | CN | disclosed |
| CN-1067655-A | FLUOROALKOXYBENZYLAMINO DERIVATIVES OF NITROGEN CONTAINING HETEROCYCLES | PFIZER (US) | 1993-01-06 | — | — | CN | disclosed |