Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 8/20 | 0.45 |
| ▸ | F10 | P00742 | 8/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 5/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | FURIN | P09958 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27295718 | 0.80 | MAOB (0.51) | MAP4K4HRH3 | |
| SCHEMBL14656296 | 0.74 | MAP4K4 (0.49) | MAP4K4KDM4EMEN1KMT2A | |
| SCHEMBL14656111 | 0.74 | THRB (0.51) | MAP4K4KDM4EMEN1KMT2A | |
| SCHEMBL27299802 | 0.74 | MAP4K4 (0.46) | ST14MAP4K4KDM4EMEN1KMT2A | |
| SCHEMBL9904964 | 0.71 | MAP4K4 (0.41) | OPRM1OPRD1OPRK1MAP4K4KDM4E | |
| SCHEMBL20364030 | 0.71 | LMNA (0.64) | F2F10ST14PRSS1PRSS2 | |
| SCHEMBL31132852 | 0.71 | MAP4K4 (0.49) | MAP4K4KDM4EMEN1KMT2A | |
| SCHEMBL27295721 | 0.71 | MAP4K4 (0.43) | MAP4K4KDM4EMEN1KMT2A | |
| SCHEMBL27299799 | 0.71 | PDE4B (0.52) | OPRM1MAP4K4KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31473353 | 0.70 | MAP4K4 (0.43) | MAP4K4KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024029489-A1 | KIT INHIBITORS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | MODULUS DISCOVERY, INC. (JP) | 2024-02-08 | — | — | WO | disclosed |