SCHEMBL27301583

SCHEMBL27301583

c1ccc(-c2cccc3ccccc23)c(-c2ccc(-c3c4ccccc4c(-c4cccc5sc6cc7ccccc7cc6c45)c4ccccc34)cc2)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.34
CA1 P00915 4/20 0.34
CA2 P00918 4/20 0.34
CA9 Q16790 4/20 0.34
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
ESR1 P03372 2/20 0.32
ESR2 Q92731 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP1 P29466 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PRKDC P78527 1/20 0.32
PIM1 P11309 1/20 0.32
PPARG P37231 5/20 0.32
PPARA Q07869 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27302620 0.93 ALDH1A1 (0.36) ESR1ESR2ALDH1A1HPGDTSHR
SCHEMBL24450616 0.92 CA12 (0.36) CA12CA1CA2CA9HDAC8
SCHEMBL27302265 0.90 ALDH1A1 (0.39) ESR1ESR2ALDH1A1HPGDTSHR
SCHEMBL27301904 0.90 S1PR5 (0.38) HDAC8ESR1ESR2
SCHEMBL27301556 0.90 CA12 (0.37) CA12CA1CA2CA9HDAC8
SCHEMBL27302939 0.89 ALOX5 (0.33) ESR1ESR2ALDH1A1HPGDF9
SCHEMBL23919365 0.88 ESR1 (0.40) CA12CA1CA2CA9ESR1
SCHEMBL18266979 0.88 ESR1 (0.42) ESR1ESR2ALDH1A1HPGDTSHR
SCHEMBL24450611 0.88 NQO1 (0.36) CA12CA1CA2CA9ALDH1A1
SCHEMBL22547509 0.87 ESR1 (0.41) CA12CA1CA2CA9ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024117761-A1 COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2024-06-06 WO disclosed