Cadaverine Tartrate — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CHRM1 CHRM2 CHRM3 CHRM4 ESR1 ESR2 GABRA1 GABRB1 GABRG2 GBA1 HRH1 HTR1D HTR2A OPRD1 OPRK1 OPRM1 SLC6A2 SLC6A3 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	CHRM1 known ✓	P11229	1/20	0.32

▸	TSHR	P16473	4/20	0.40

▸	CYP2C19	P33261	2/20	0.40

▸	NFKB1	P19838	1/20	0.40

▸	HSD17B10	Q99714	2/20	0.39

▸	CYP1A2	P05177	3/20	0.35

▸	TDP1	Q9NUW8	2/20	0.35

▸	POLB	P06746	1/20	0.34

▸	MEN1	O00255	1/20	0.34

▸	KMT2A	Q03164	1/20	0.34

▸	AOC3	Q16853	1/20	0.33

▸	TFPI2	P48307	1/20	0.33

▸	GAA	P10253	1/20	0.33

▸	CYP2D6	P10635	2/20	0.32

▸	LMNA	P02545	1/20	0.32

▸	PKM	P14618	1/20	0.32

▸	ALDH1A1	P00352	1/20	0.32

▸	CYP3A4	P08684	1/20	0.32

▸	CYP2C9	P11712	1/20	0.32

▸	HPGD	P15428	2/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Cadaverine Tartrate SCHEMBL30823605	0.83	HSD17B10 (0.48)	TSHRCYP2C19NFKB1HSD17B10TDP1
SCHEMBL29178251	0.80	TDP1 (0.38)	TSHRHSD17B10CYP1A2TDP1POLB
SCHEMBL273020	0.80	—	—
Formic Acid SCHEMBL29763161	0.78	CYP1A2 (0.39)	TSHRHSD17B10CYP1A2TDP1POLB
Bromide SCHEMBL16765046	0.78	TDP1 (0.36)	TSHRHSD17B10CYP1A2TDP1POLB
Hydrochloric Acid SCHEMBL3831383	0.78	TDP1 (0.36)	TSHRHSD17B10CYP1A2TDP1POLB
Cadaverine Tartrate SCHEMBL1574315	0.76	TSHR (0.52)	TSHRCYP2C19NFKB1CYP1A2TDP1
Trifluoroacetic Acid SCHEMBL28965161	0.76	CHRM1 (0.36)	TSHRHSD17B10CYP1A2TDP1POLB
SCHEMBL295238	0.73	HSD17B10 (0.38)	HSD17B10CYP1A2TDP1KMT2ALMNA
Cadaverine Tartrate SCHEMBL30171032	0.71	TSHR (0.43)	TSHRCYP2C19NFKB1CYP1A2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20090137600-A1	Antiplatelet agent and process for producing the same	DAIICHI PHARMACEUTICAL CO., LTD. (JP)	2009-05-28	—	—	US	disclosed
EP-1775293-A1	ANTIPLATELET AGENT AND PROCESS FOR PRODUCING THE SAME	DAIICHI PHARMACEUTICAL CO., LTD. (JP)	2007-04-18	—	—	EP	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20090137600-A1	Antiplatelet agent and process for producing the same	PFKP, GP6, PF4	CHRM1 3569/4885TSHR 2922/4885CYP2C19 39/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.