Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28965161

CN1CCN(C=O)CC1.O=C(O)C(F)(F)F

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 6/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CYP1A2 P05177 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HRH4 Q9H3N8 2/20 0.35
HRH3 Q9Y5N1 2/20 0.35
CXCR2 P25025 2/20 0.34
POLB P06746 2/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.33
TFPI2 P48307 1/20 0.33
HPGD P15428 2/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL23292174 0.85 CYP1A2 (0.46) CHRM1CHRM4CHRM5CYP1A2TDP1
Trifluoroacetic Acid SCHEMBL28918734 0.84 ACHE (0.38) HRH3
Trifluoroacetic Acid SCHEMBL28709650 0.83 HSD17B10 (0.39) CHRM1CHRM4CHRM5TSHRHSD17B10
Trifluoroacetic Acid SCHEMBL30636582 0.81 HSD17B10 (0.42) POLBTSHRHSD17B10TFPI2HPGD
SCHEMBL273020 0.80
SCHEMBL29178251 0.80 TDP1 (0.38) CHRM1CHRM4CHRM5CYP1A2TDP1
Trifluoroacetic Acid SCHEMBL23932396 0.78 LMNA (0.36) TSHR
Trifluoroacetic Acid SCHEMBL2265273 0.78 HRH4 (0.39) CHRM1CHRM4CHRM5CYP1A2TDP1
Formic Acid SCHEMBL29763161 0.78 CYP1A2 (0.39) CYP1A2TDP1POLBTSHRHSD17B10
Trifluoroacetic Acid SCHEMBL28623741 0.78 ALDH1A1 (0.40) POLBTSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115715289-B Polyarylate and application thereof 江苏先声药业有限公司 2024-12-03 CN disclosed
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. 2023-10-05 US disclosed
CN-115715289-A Polyarylate and use thereof 江苏先声药业有限公司 2023-02-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS LOX, LOXL1, LOXL2 CHRM1 1352/4885CHRM4 1917/4885CHRM5 1434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.