Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730229 | 1.00 | TRPM8 (0.49) | TRPM8BCHEMAOAACHEMAOB | |
| SCHEMBL30582813 | 1.00 | TRPM8 (0.49) | TRPM8BCHEMAOAACHEMAOB | |
| SCHEMBL30582799 | 0.81 | SNCA (0.47) | TRPM8BCHEMAOAACHEMAOB | |
| SCHEMBL2730615 | 0.81 | TRPM8 (0.75) | TRPM8NPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL2730551 | 0.81 | SNCA (0.47) | TRPM8BCHEMAOAACHEMAOB | |
| SCHEMBL2730548 | 0.81 | SNCA (0.47) | TRPM8BCHEMAOAACHEMAOB | |
| SCHEMBL2730618 | 0.81 | TRPM8 (0.75) | TRPM8NPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL2719629 | 0.81 | TRPM8 (0.60) | TRPM8BCHEMAOAACHEMAOB | |
| SCHEMBL2719625 | 0.81 | TRPM8 (0.60) | TRPM8BCHEMAOAACHEMAOB | |
| SCHEMBL2729533 | 0.79 | TRPM8 (0.68) | TRPM8NPC1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3478089-A1 | PLATED YEAST FORMULATIONS | Firmenich SA (CH) | 2019-05-08 | — | — | EP | disclosed |
| WO-2018002331-A1 | PLATED YEAST FORMULATIONS | FIRMENICH SA (CH) | 2018-01-04 | — | — | WO | disclosed |
| EP-2635572-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012061698-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012061698-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-05-10 | — | — | WO | disclosed |