Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 3/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL507660 | 0.79 | NTRK1 (0.56) | EGLN2VNN1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1882080 | 0.78 | SMN1; SMN2 (0.68) | MAP4K4VNN1NPC1PKMRAB9A | |
| SCHEMBL1267858 | 0.77 | CYP3A4 (0.55) | EGLN2NTRK3CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL32683749 | 0.77 | IDH1 (0.44) | IDH1VNN1MEN1KMT2ANTRK1 | |
| SCHEMBL27304831 | 0.75 | NPC1 (0.58) | IDH1NPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL1882774 | 0.75 | VNN1 (0.47) | MAP4K4VNN1NPC1PKMRAB9A | |
| SCHEMBL27304412 | 0.75 | NTRK1 (0.61) | EGLN2MAP4K4LRRK2VNN1NTRK1 | |
| SCHEMBL27302479 | 0.75 | MEN1 (0.54) | SMN1; SMN2MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL6638863 | 0.74 | DPP4 (0.53) | IDH1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL29580404 | 0.73 | ALDH1A1 (0.65) | MAP4K4NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024029489-A1 | KIT INHIBITORS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | MODULUS DISCOVERY, INC. (JP) | 2024-02-08 | — | — | WO | disclosed |