Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9051750 | 0.83 | MAOA (0.33) | MAOAMAOB | |
| SCHEMBL5110375 | 0.83 | MAPT (0.47) | MAPTKDM4EHPGDTP53POLB | |
| SCHEMBL9358742 | 0.73 | MAPT (0.44) | MAPTKDM4EMAOATP53ACHE | |
| SCHEMBL5132106 | 0.72 | MAPT (0.50) | MAPTKDM4EPOLBGAAACHE | |
| SCHEMBL12015997 | 0.69 | MAOA (0.68) | MAPTKDM4EMAOATDP1MAOB | |
| SCHEMBL8648306 | 0.69 | MAPT (0.41) | MAPTKDM4EMAOAMAOBHTR2A | |
| SCHEMBL12016000 | 0.68 | MAPT (0.40) | MAPT | |
| SCHEMBL14675631 | 0.67 | — | — | |
| SCHEMBL5572028 | 0.67 | CCR1 (0.32) | — | |
| SCHEMBL11470096 | 0.64 | MAOA (0.45) | MAPTKDM4EMAOAACHETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1031754-C | Dithiane | HOFFMANN LA ROCHE (CH) | 1996-05-08 | — | — | CN | disclosed |
| CN-1068569-A | DITHIANE | HOFFMANN LA ROCHE (CH) | 1993-02-03 | — | — | CN | disclosed |