Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648816 | 0.81 | MAPT (0.41) | MAPTKDM4EMAOBHTR2CHTR2B | |
| SCHEMBL7297943 | 0.81 | KDM1A (0.34) | MAPTKDM4EBCHEHTR2AHTR2C | |
| SCHEMBL8647431 | 0.81 | LMNA (0.33) | KDM4EHTR2AHTR2CHTR2B | |
| SCHEMBL4175988 | 0.81 | BRD4 (0.34) | MAPTMAOANISCHMAOB | |
| SCHEMBL9358742 | 0.71 | MAPT (0.44) | MAPTMAOAKDM4EMAOBHTR2A | |
| SCHEMBL5110375 | 0.71 | MAPT (0.47) | MAPTKDM4EBCHEHTR2AHTR2C | |
| SCHEMBL1366298 | 0.67 | SLC18A3 (0.38) | MAPTHTR2AHTR2CHTR2B | |
| SCHEMBL12015997 | 0.67 | MAOA (0.68) | MAPTMAOAKDM4EMAOB | |
| SCHEMBL12016000 | 0.66 | MAPT (0.40) | MAPT | |
| SCHEMBL5132106 | 0.65 | MAPT (0.50) | MAPTKDM4EHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |