Urea

Urea

SCHEMBL27306115

CCCCc1ccccc1O.NC(N)=O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 5/20 0.53
MCL1 Q07820 5/20 0.53
BCL2L1 Q07817 4/20 0.53
BAK1 Q16611 4/20 0.53
KAT8 Q9H7Z6 2/20 0.53
SAE1 Q9UBE0 2/20 0.53
PPARG P37231 1/20 0.53
PPARA Q07869 1/20 0.53
EP300 Q09472 1/20 0.53
KAT2A Q92830 1/20 0.53
KAT2B Q92831 1/20 0.53
KAT5 Q92993 1/20 0.53
TAAR1 Q96RJ0 1/20 0.52
HTR1A P08908 1/20 0.51
TSHR P16473 1/20 0.51
TYR P14679 1/20 0.50
IAPP P10997 1/20 0.49
MGLL Q99685 1/20 0.47
MPO P05164 1/20 0.47
SLC6A4 P31645 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL27303041 0.96 BID (0.50) BIDMCL1BCL2L1BAK1KAT8
Urea SCHEMBL27750272 0.93 BID (0.62) BIDMCL1BCL2L1BAK1KAT8
Urea SCHEMBL28059627 0.93 BID (0.62) BIDMCL1BCL2L1BAK1KAT8
Urea SCHEMBL27256262 0.93 BID (0.62) BIDMCL1BCL2L1BAK1KAT8
Urea SCHEMBL27533207 0.91 BID (0.56) BIDMCL1BCL2L1BAK1KAT8
Isobutyramide SCHEMBL28186861 0.91 BID (0.49) BIDMCL1BCL2L1BAK1KAT8
Urea SCHEMBL28176710 0.91 BID (0.60) BIDMCL1BCL2L1BAK1KAT8
Acetone SCHEMBL25277794 0.91 BID (0.54) BIDMCL1BCL2L1BAK1KAT8
Bicarbonate SCHEMBL4267974 0.91 BID (0.58) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL29450060 0.90 HTR1A (0.60) BIDMCL1BCL2L1BAK1KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1058980-A Be used for rubber and plastic and cement sheeting agglutinating binding agent RUBBER AXIS FACTORY TENGZHOU C (CN) 1992-02-26 CN claimed
CN-109320808-A A kind of sole and preparation method thereof of included plybonding effect 鹤山市金俊达新材料有限公司 2019-02-12 CN disclosed
CN-103319686-B The production technique of high-performance poly isocyanate glue CHANGSHU CITY, GANGNAM STATION AGENT CO., LTD. (CN) 2015-07-29 CN disclosed
CN-103570937-A Phenolic resin/MC nylon composite material, and preparation method thereof HEFEI GENIUS NEW MAT CO LTD 2014-02-12 CN disclosed
CN-103320080-A Polyisocyanate adhesive production process CHANGSHU CITY GANGNAM STATION AGENT CO LTD 2013-09-25 CN disclosed
CN-103319686-A High-performance polyisocyanate adhesive production process CHANGSHU CITY GANGNAM STATION AGENT CO LTD 2013-09-25 CN disclosed
CN-101180385-B Lubricating oil composition with reduced phosphorus levels ALBEMARLE CORP 2012-10-10 CN disclosed
CN-101180385-A Lubricating oil composition with reduced phosphorus levels ALBEMARLE CORP (US) 2008-05-14 CN disclosed
CN-100343352-C Stick-proof anti corrosion paint for internal wall of water steam pipeline LANZHOU CHEM PHYS INST (CN) 2007-10-17 CN disclosed
CN-1724601-A Antisticking corrosion-proof paint in the steam pipeline LANZHOU CHEM PHYS INST (CN) 2006-01-25 CN disclosed
CN-1031511-C Non-polar adhesive JIANG HUANENG (CN) 1996-04-10 CN disclosed
CN-1058980-A Be used for rubber and plastic and cement sheeting agglutinating binding agent RUBBER AXIS FACTORY TENGZHOU C (CN) 1992-02-26 CN disclosed