Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | CASP6 | P55212 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.50 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1237049 | 1.00 | NT5E (0.66) | NT5EALDH1A1CASP6HSD17B10CYP2C9 | |
| SCHEMBL11426409 | 1.00 | NT5E (0.66) | NT5EALDH1A1CASP6HSD17B10CYP2C9 | |
| Water SCHEMBL21802350 | 0.98 | NT5E (0.64) | NT5EALDH1A1CASP6HSD17B10CYP2C9 | |
| SCHEMBL29610078 | 0.98 | NT5E (0.68) | NT5EALDH1A1CASP6HSD17B10CYP2C9 | |
| SCHEMBL29429619 | 0.98 | NT5E (0.68) | NT5EALDH1A1CASP6HSD17B10CYP2C9 | |
| SCHEMBL11426413 | 0.98 | NT5E (0.68) | NT5EALDH1A1CASP6HSD17B10CYP2C9 | |
| SCHEMBL30566330 | 0.98 | NT5E (0.68) | NT5EALDH1A1CASP6HSD17B10CYP2C9 | |
| SCHEMBL152377 | 0.98 | NT5E (0.68) | NT5EALDH1A1CASP6HSD17B10CYP2C9 | |
| SCHEMBL2730688 | 0.98 | NT5E (0.68) | NT5EALDH1A1CASP6HSD17B10CYP2C9 | |
| SCHEMBL31229304 | 0.98 | NT5E (0.68) | NT5EALDH1A1CASP6HSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200171005-A9 | Heterobifunctional Pan-Selectin Antagonists Having a Triazole Linker | GLYCOMIMETICS, INC. (US) | 2020-06-04 | — | — | US | disclosed |
| US-20180369205-A1 | Heterobifunctional Pan-Selectin Antagonists Having a Triazole Linker | GLYCOMIMETICS, INC. (US) | 2018-12-27 | — | — | US | disclosed |
| EP-3383882-A1 | HETEROBIFUNCTIONAL PAN-SELECTIN ANTAGONISTS HAVING A TRIAZOLE LINKER | GlycoMimetics, Inc. (US) | 2018-10-10 | — | — | EP | disclosed |
| WO-2017095904-A1 | HETEROBIFUNCTIONAL PAN-SELECTIN ANTAGONISTS HAVING A TRIAZOLE LINKER | GLYCOMIMETICS, INC. (US) | 2017-06-08 | — | — | WO | disclosed |
| US-8796323-B2 | Defensin-like molecules as novel antimicrobial agents | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2014-08-05 | — | — | US | disclosed |
| US-20130231376-A1 | DEFENSIN-LIKE MOLECULES AS NOVEL ANTIMICROBIAL AGENTS | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2013-09-05 | — | — | US | disclosed |
| WO-2012061767-A2 | DEFENSIN-LIKE MOLECULES AS NOVEL ANTIMICROBIAL AGENTS | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2012-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130231376-A1 | DEFENSIN-LIKE MOLECULES AS NOVEL ANTIMICROBIAL AGENTS | DBNL, DNASE1L3, STING1 | NT5E 452/4885ALDH1A1 2828/4885CASP6 1573/4885 |
| US-20200171005-A9 | Heterobifunctional Pan-Selectin Antagonists Having a Triazole Linker | SELE, SELP, SELPLG | NT5E 2199/4885ALDH1A1 391/4885CASP6 3354/4885 |
| US-20180369205-A1 | Heterobifunctional Pan-Selectin Antagonists Having a Triazole Linker | SELE, SELP, SELPLG | NT5E 2199/4885ALDH1A1 391/4885CASP6 3354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.