Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MGAT2 | Q10469 | 3/20 | 0.32 |
| ▸ | MGAT1 | P26572 | 2/20 | 0.32 |
| ▸ | MGAT3 | Q09327 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | STK10 | O94804 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27306826 | 0.88 | NPSR1 (0.33) | MGAT2MGAT1MGAT3APPNPSR1 | |
| SCHEMBL27306821 | 0.83 | STK10 (0.36) | MGAT2MGAT1MGAT3APPNPSR1 | |
| SCHEMBL27307055 | 0.83 | MGAT1 (0.31) | MGAT2MGAT1MGAT3APPNPSR1 | |
| SCHEMBL27306369 | 0.75 | APP (0.32) | MAPK13MAPK12MAPK11MAPK14APP | |
| SCHEMBL27305898 | 0.74 | ALDH1A1 (0.42) | MAPK13MAPK12MAPK11MAPK14APP | |
| SCHEMBL27306928 | 0.72 | EGFR (0.38) | MGAT2MGAT1MGAT3NPSR1HPGD | |
| SCHEMBL27307388 | 0.71 | HTT (0.33) | MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL27307391 | 0.70 | ALDH1A1 (0.39) | HPGDMEN1KMT2ALMNAMAPT | |
| SCHEMBL27307053 | 0.68 | MEN1 (0.31) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL27307057 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235855-A1 | QUINOLINEAMINE ANTIDEGRADANT COMPOUNDS AND USES THEREOF | FLEXSYS AMERICA L.P. (US) | 2023-12-07 | — | — | WO | disclosed |