Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.30 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | STK10 | O94804 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27306239 | 0.87 | APP (0.35) | APP | |
| SCHEMBL27306358 | 0.87 | APP (0.32) | APP | |
| SCHEMBL27306478 | 0.84 | APP (0.30) | APP | |
| SCHEMBL27306242 | 0.84 | STK10 (0.36) | APPSTK10GSK3BSLK | |
| SCHEMBL27305898 | 0.76 | ALDH1A1 (0.42) | APPMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL27306933 | 0.75 | MAPK13 (0.33) | APPMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL27306728 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL27306365 | 0.71 | EGFR (0.37) | — | |
| SCHEMBL27306816 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL27306481 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235855-A1 | QUINOLINEAMINE ANTIDEGRADANT COMPOUNDS AND USES THEREOF | FLEXSYS AMERICA L.P. (US) | 2023-12-07 | — | — | WO | disclosed |