Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 6/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FADS1 | O60427 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27736388 | 0.80 | KDM4E (0.35) | HTTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL27697478 | 0.70 | KDM4E (0.47) | SMN1; SMN2HTTLMNAKDM4EALDH1A1 | |
| SCHEMBL27850019 | 0.70 | EGFR (0.48) | EGFR | |
| SCHEMBL27877333 | 0.67 | — | — | |
| SCHEMBL29205283 | 0.66 | KDM4E (0.54) | SMN1; SMN2HTTLMNAKDM4EALDH1A1 | |
| SCHEMBL11846406 | 0.64 | KDM4E (0.63) | SMN1; SMN2HTTLMNAKDM4EALDH1A1 | |
| SCHEMBL28944682 | 0.64 | MAPT (0.42) | HTT | |
| SCHEMBL11090480 | 0.63 | KDM4E (0.66) | LMNAKDM4EALDH1A1EGFRMEN1 | |
| SCHEMBL4740533 | 0.63 | EGFR (0.82) | SMN1; SMN2HTTLMNAKDM4EALDH1A1 | |
| SCHEMBL28804032 | 0.63 | PIN1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1034924-A | quinoline, quinazoline and cinnoline derivatives | LILLY CO ELI (US) | 1989-08-23 | — | — | CN | disclosed |