Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | KMO | O15229 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27307115 | 0.91 | HDAC4 (0.50) | HDAC4HDAC2HDAC8KMOMDM2 | |
| SCHEMBL5667650 | 0.78 | KMO (0.64) | HDAC4HDAC2HDAC8KMOEPHX2 | |
| SCHEMBL669730 | 0.78 | KMO (0.64) | HDAC4HDAC2HDAC8KMOEPHX2 | |
| SCHEMBL26936966 | 0.77 | KMO (0.53) | HDAC4HDAC2HDAC8KMOEPHX2 | |
| SCHEMBL21471492 | 0.76 | HDAC4 (0.96) | HDAC4HDAC2HDAC8KMOEPHX2 | |
| SCHEMBL5666805 | 0.75 | KMO (0.62) | HDAC4HDAC2HDAC8KMOEPHX2 | |
| SCHEMBL778529 | 0.75 | HDAC4 (0.63) | HDAC4HDAC2HDAC8KMOCYP11B2 | |
| SCHEMBL21471491 | 0.74 | HDAC4 (1.00) | HDAC4HDAC2HDAC8KMOACMSD | |
| Hydrogen Peroxide SCHEMBL11391460 | 0.73 | KMO (0.71) | HDAC4HDAC2HDAC8KMOCYP11B2 | |
| SCHEMBL21471547 | 0.72 | HDAC4 (0.72) | HDAC4HDAC2HDAC8KMOEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073131-A2 | METHOD OF TREATING NEURODEGENERATIVE DISEASES | THE BOARD OF TRUSTEES OF THE UNIVESITY OF ILLINOIS (US) | 2024-04-04 | — | — | WO | disclosed |