Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5667650 | 0.82 | KMO (0.64) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| SCHEMBL669730 | 0.82 | KMO (0.64) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| SCHEMBL22966418 | 0.81 | KMO (0.49) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| SCHEMBL11344825 | 0.81 | KMO (0.49) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| SCHEMBL5666805 | 0.80 | KMO (0.62) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| SCHEMBL778529 | 0.79 | HDAC4 (0.63) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| Hydrogen Peroxide SCHEMBL11391460 | 0.78 | KMO (0.71) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| SCHEMBL27307116 | 0.77 | HDAC4 (0.58) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| SCHEMBL2097266 | 0.75 | KMO (0.58) | KMOHDAC4HDAC2HDAC8CYP11B2 | |
| SCHEMBL19446564 | 0.74 | HDAC8 (0.46) | HDAC8ACMSDHSP90AA1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289823-A1 | SUBSTITUTED PYRIDAZINE PHENOL DERIVATIVES | Medshine Discovery Inc. (CN) | 2023-12-13 | — | — | EP | disclosed |