SCHEMBL27308232

SCHEMBL27308232

CC(O)Oc1ccc(SOSc2ccc(OC(C)O)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.37
KMT2A Q03164 1/20 0.34
CYP1A2 P05177 2/20 0.32
GAA P10253 2/20 0.32
CYP2C19 P33261 2/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
PKM P14618 1/20 0.32
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
TAS1R2 Q8TE23 1/20 0.32
POLB P06746 1/20 0.32
ALDH1A3 P47895 1/20 0.31
PTGIR P43119 1/20 0.31
GLA P06280 1/20 0.31
RAB9A P51151 1/20 0.30
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL890769 0.83 LMNA (0.42) PARP10KMT2ACYP1A2GAACYP2C19
SCHEMBL97898 0.82 PARP10 (0.48) PARP10KMT2ACYP1A2GAACYP2C19
SCHEMBL17961880 0.82 PARP10 (0.48) PARP10KMT2ACYP1A2GAACYP2C19
SCHEMBL10977168 0.82 PARP10 (0.48) PARP10KMT2ACYP1A2GAACYP2C19
SCHEMBL5243106 0.81 CYP1A1 (0.42) PARP10CYP1A2
SCHEMBL9814077 0.75 CYP1A2 (0.50) PARP10KMT2ACYP1A2GAACYP2C19
SCHEMBL10795235 0.73 HTT (0.33) PARP10KMT2ACYP1A2GAACYP2C19
SCHEMBL10425031 0.73 PARP10 (0.41) PARP10KMT2ACYP1A2GAACYP2C19
SCHEMBL6061597 0.73 ESR2 (0.48) PARP10KMT2ARAB9ALMNA
SCHEMBL7521294 0.73 ACHE (0.46) PARP10KMT2APOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1092211-C Method for preparing plastic lens containing high-refractivity resin MITSUI CHEMICALS INC (JP) 2002-10-09 CN disclosed
CN-1069331-C Process for producing finished product of plastic lens MITSUI CHEMICALS INC (JP) 2001-08-08 CN disclosed
CN-1036463-C Aprocess for preparing a resin having a large refractive index MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-19 CN disclosed
CN-1149066-A Process for producing finished product of plastic lens MITSUI TOATSU CHEMICALS (JP) 1997-05-07 CN disclosed
CN-1098723-A Preparation has the method for high refractive index resins MITSUI TOATSU CHEMICALS (JP) 1995-02-15 CN disclosed
CN-1039429-A Resin having high refractive index, lens comprising the resin, and method for producing the lens MITSUI TOATSU CHEMICALS (JP) 1990-02-07 CN disclosed