Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.40 |
| ▸ | HNF4A | P41235 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27672222 | 0.87 | LDHA (0.54) | LDHACCR2ESR1ESR2ACMSD | |
| SCHEMBL8679771 | 0.80 | KDR (0.49) | PDGFRBKDRCCR2MCL1ALDH1A1 | |
| SCHEMBL27265492 | 0.78 | KDR (0.48) | PDGFRBKDRCCR2MCL1ALDH1A1 | |
| SCHEMBL27278555 | 0.70 | MEN1 (0.50) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL7493338 | 0.70 | LDHA (0.42) | LDHACCR2IKBKBKDM4EALDH1A1 | |
| SCHEMBL28193714 | 0.69 | KDR (0.72) | PDGFRBKDRKDM4EALDH1A1HPGD | |
| SCHEMBL7814 | 0.68 | LDHA (1.00) | LDHACCR2ACMSDHNF4ADHFR | |
| SCHEMBL7300 | 0.68 | LDHA (1.00) | LDHACCR2ACMSDHNF4ADHFR | |
| Hydrochloric Acid SCHEMBL28194245 | 0.68 | KDR (0.70) | PDGFRBKDRKDM4EALDH1A1HPGD | |
| SCHEMBL5250297 | 0.68 | CHEK1 (0.41) | KDRKDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1008733-B | Be used as the preparation of 2-oxyindole-1-methane amide that the 3-of anodyne and antiphlogistic replaces | PFIZER (US) | 1990-07-11 | — | — | CN | disclosed |
| CN-1007428-B | PROCESS FOR MAKING 2-OXINDOLE-1-CARBOXAMIDES AND INTERMEDIATES THEREFOR | PFIZER (US) | 1990-04-04 | — | — | CN | disclosed |
| CN-85101029-A | The method of preparation-2-oxyindole-1-methane amide and intermediate product thereof | — | 1987-01-24 | — | — | CN | disclosed |
| CN-85101028-A | Be used as the preparation of 2-oxyindole-1-methane amide that the 3-of anodyne and antiphlogistic replaces | — | 1987-01-17 | — | — | CN | disclosed |