Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 13/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 10/20 | 0.49 |
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27265492 | 0.98 | KDR (0.48) | KDRPDGFRBDAOSLC9A1MCL1 | |
| SCHEMBL4467286 | 0.82 | DAO (0.47) | KDRPDGFRBDAOMCL1ALDH1A1 | |
| SCHEMBL17022579 | 0.81 | POLB (0.52) | DAOSLC9A1MCL1ALDH1A1TSHR | |
| SCHEMBL27308385 | 0.80 | LDHA (0.51) | KDRPDGFRBMCL1ALDH1A1CCR2 | |
| SCHEMBL31122079 | 0.79 | KDR (0.51) | KDRPDGFRBSLC9A1MCL1ALDH1A1 | |
| SCHEMBL27597857 | 0.79 | KDR (0.51) | KDRPDGFRBDAOSLC9A1MCL1 | |
| SCHEMBL8360588 | 0.79 | KDR (0.51) | KDRPDGFRBSLC9A1MCL1ALDH1A1 | |
| SCHEMBL17022686 | 0.78 | SRC (0.53) | DAOMCL1TSHR | |
| Benzene SCHEMBL28136154 | 0.78 | KDR (0.50) | KDRPDGFRBDAOSLC9A1MCL1 | |
| Hydrochloric Acid SCHEMBL28136871 | 0.78 | KDR (0.50) | KDRPDGFRBSLC9A1MCL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1093704-A | Regioselective synthesis of 4-chloro-2-thiophenecarboxylic acid | PFIZER (US) | 1994-10-19 | — | — | CN | claimed |
| CN-85103527-A | Preparation N, the method for the disubstituted 2-hydroxyindole of 3--1-hydroxyalkyl cooh amide | — | 1987-01-28 | — | — | CN | claimed |
| JP-10087614-A | — | — | None | — | — | JP | disclosed |
| JP-4235165-A | — | — | None | — | — | JP | disclosed |
| JP-H1087614-A | STABLE AND LONG-TIME ACTING SALT OF CARBOXAMIDE FOR CURING ARTICULAR DISEASE | PFIZER INC | 1998-04-07 | — | — | JP | disclosed |
| WO-1997022605-A1 | STABLE, LONG ACTING SALTS OF INDOLE DERIVATIVES FOR THE TREATMENT OF JOINT DISEASES | PFIZER INC. (US) | 1997-06-26 | — | — | WO | disclosed |
| CN-1136921-A | Pharmaceutical agents for treatment of alzheimer's disease | PFIZER (US) | 1996-12-04 | — | — | CN | disclosed |
| CN-1123144-A | 3-substituted-2-oxindoles as inhibitors of viral replication | PFIZER (US) | 1996-05-29 | — | — | CN | disclosed |
| CN-1099614-A | 6-chloro-5-fluoro-3-(2-thenoyl)-2-oxindole-1-carboxamide as an analgesic and anti-inflammatory agent | PFIZER (US) | 1995-03-08 | — | — | CN | disclosed |
| CN-1093704-A | Regioselective synthesis of 4-chloro-2-thiophenecarboxylic acid | PFIZER (US) | 1994-10-19 | — | — | CN | disclosed |
| CN-1022324-C | Anhydrous crystal sodium salt of 5-chloro-3-(2-thenoyl)-2-oxyindole-1-carboxamide | PFIZER (US) | 1993-10-06 | — | — | CN | disclosed |
| CN-1003855-B | Process for preparing 1, 3-disubstituted 2-oxindoles | 美国辉瑞有限公司 | 1989-04-12 | — | — | CN | disclosed |
| CN-1003855-B | Process for preparing 1, 3-disubstituted 2-oxindoles | 美国辉瑞有限公司 | 1989-04-12 | — | — | CN | disclosed |
| CN-88100555-A | Anhydrous, crystalline sodium salt of 5-chloro-3- (2-thenoyl) -2-hydroxyindole-1-carboxamide | — | 1988-08-17 | — | — | CN | disclosed |
| CN-85101795-A | With 1, the two 2-oxyindoles that replace of 3-prepare pain killer and antiphlogistic | — | 1987-04-08 | — | — | CN | disclosed |
| CN-85103527-A | Preparation N, the method for the disubstituted 2-hydroxyindole of 3--1-hydroxyalkyl cooh amide | — | 1987-01-28 | — | — | CN | disclosed |
| CN-85103527-A | Preparation N, the method for the disubstituted 2-hydroxyindole of 3--1-hydroxyalkyl cooh amide | — | 1987-01-28 | — | — | CN | disclosed |
| CN-85101029-A | The method of preparation-2-oxyindole-1-methane amide and intermediate product thereof | — | 1987-01-24 | — | — | CN | disclosed |
| CN-85101028-A | Be used as the preparation of 2-oxyindole-1-methane amide that the 3-of anodyne and antiphlogistic replaces | — | 1987-01-17 | — | — | CN | disclosed |
| CN-85101028-A | Be used as the preparation of 2-oxyindole-1-methane amide that the 3-of anodyne and antiphlogistic replaces | — | 1987-01-17 | — | — | CN | disclosed |