Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 3/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL226527 | 0.80 | HTR2C (0.40) | MEN1KMT2AGAALMNAPOLB | |
| SCHEMBL3662388 | 0.80 | HTR2C (0.40) | MEN1KMT2AGAALMNAPOLB | |
| SCHEMBL226255 | 0.80 | HTR2C (0.40) | MEN1KMT2AGAALMNAPOLB | |
| SCHEMBL4915463 | 0.79 | KMT2A (0.41) | MEN1KMT2AGAALMNAPOLB | |
| SCHEMBL7494216 | 0.79 | ALDH1A1 (0.40) | KMT2AGAALMNAPOLBOXTR | |
| SCHEMBL4915454 | 0.79 | KMT2A (0.41) | MEN1KMT2AGAALMNAPOLB | |
| SCHEMBL12184848 | 0.77 | LMNA (0.41) | MEN1KMT2ALMNAPOLBOXTR | |
| SCHEMBL283816 | 0.75 | LMNA (0.38) | MEN1KMT2AGAALMNAPOLB | |
| SCHEMBL283815 | 0.75 | LMNA (0.38) | MEN1KMT2AGAALMNAPOLB | |
| SCHEMBL10080310 | 0.72 | HTR2C (0.35) | MEN1KMT2ALMNAPOLBOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015262-A1 | FUSED RING KRAS INHIBITORS FOR TREATING DISEASE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | WO | disclosed |