SCHEMBL27312136

SCHEMBL27312136

CC(C)c1csnc1OC1CCCC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LRRK2 Q5S007 4/20 0.33
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
JAK3 P52333 2/20 0.31
HRH4 Q9H3N8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24224724 0.69 LRRK2 (0.43) LRRK2JAK3
SCHEMBL23620145 0.65 LRRK2 (0.46) LRRK2JAK3
SCHEMBL21737319 0.64
SCHEMBL15077043 0.63 PDE4A (0.42)
SCHEMBL22426537 0.62 CARM1 (0.43)
SCHEMBL17972910 0.62 CARM1 (0.43)
SCHEMBL25144094 0.62 LRRK2 (0.43) LRRK2
SCHEMBL4546379 0.61
SCHEMBL22041240 0.61 PDE10A (0.39) LRRK2
SCHEMBL25484244 0.60 ALDH1A1 (0.44) PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024059010-A1 COMPOUNDS FOR TREATING CANCER GENESIS THERAPEUTICS, INC. (US) 2024-03-21 WO disclosed