Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15304590 | 0.83 | MEN1 (0.40) | SMN1; SMN2MEN1KMT2ANPSR1LMNA | |
| SCHEMBL27499691 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2ANPSR1LMNA | |
| SCHEMBL27879785 | 0.78 | TP53 (0.41) | TP53 | |
| SCHEMBL28409641 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL27841572 | 0.78 | CHRNB4 (0.39) | ALDH1A1TP53HPGDCHRNB4CHRNA3 | |
| SCHEMBL27517106 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2ANPSR1LMNA | |
| SCHEMBL27520107 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2MEN1KMT2ANPSR1LMNA | |
| Hydrochloric Acid SCHEMBL29080929 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL680143 | 0.75 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL15222055 | 0.75 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744476-B | IMIDAZOPYRAZINE Syk INHIBITORS | 吉利德康涅狄格公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-1215595-C | Nonaqueous electrolyte and secondary battery using the same | MITSUBISHI CHEM CORP (JP) | 2005-08-17 | — | — | CN | disclosed |
| CN-1465117-A | Nonaqueous electrolyte and secondary battery using the same | MITSUBISHI CHEM CORP (JP) | 2003-12-31 | — | — | CN | disclosed |
| CN-1032479-A | Replace azoles and its method for making of piperazine compounds and weeding purpose | SCHERING AG (DE) | 1989-04-26 | — | — | CN | disclosed |