Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28222599 | 0.92 | ALDH1A1 (0.48) | FOLH1ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL13996825 | 0.92 | ALDH1A1 (0.48) | FOLH1ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL26047547 | 0.89 | ALDH1A1 (0.49) | FOLH1ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL22300310 | 0.86 | ALDH1A1 (0.49) | FOLH1ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL27847367 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AHPGDMAPK1 | |
| SCHEMBL27452709 | 0.86 | ALDH1A1 (0.50) | FOLH1ALDH1A1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL24591318 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AHPGDMAPK1 | |
| SCHEMBL24235586 | 0.83 | MEN1 (0.53) | ALDH1A1MEN1KMT2AHPGDMAPK1 | |
| SCHEMBL12626917 | 0.83 | FOLH1 (0.54) | FOLH1ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL22356651 | 0.83 | FOLH1 (0.54) | FOLH1ALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1032858-C | Methylamino pterin derivatives | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1996-09-25 | — | — | CN | disclosed |
| CN-1078968-A | 2-Piperazinone compounds and their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-01 | — | — | CN | disclosed |
| CN-1069730-A | 2-Piperazinone compounds and their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-03-10 | — | — | CN | disclosed |
| CN-1059725-A | Novel methotrexate derivatives | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1992-03-25 | — | — | CN | disclosed |