Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27572427 | 0.91 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 | |
| SCHEMBL27312654 | 0.86 | FOLH1 (0.49) | ALDH1A1MAPK1L3MBTL1CASP1CYP1A2 | |
| SCHEMBL27692552 | 0.83 | MMP9 (0.44) | ALDH1A1MAPK1L3MBTL1MMP9KMT2A | |
| SCHEMBL13936459 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 | |
| SCHEMBL13412924 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 | |
| SCHEMBL24633781 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 | |
| SCHEMBL17995311 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 | |
| SCHEMBL16446118 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 | |
| SCHEMBL23901564 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 | |
| SCHEMBL9448685 | 0.82 | SLC15A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102365294-B | The dipeptide analogue of neurotrophic factor NGF and BDNF | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUKNAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII IMENI V.V.ZAKUSOVA RAMN (RU) | 2016-02-17 | — | — | CN | disclosed |
| CN-102365294-A | Dipeptide mimetics of ngf and bdnf neurotrophins | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUK | 2012-02-29 | — | — | CN | disclosed |
| CN-1078968-A | 2-Piperazinone compounds and their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-01 | — | — | CN | disclosed |
| CN-1069730-A | 2-Piperazinone compounds and their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-03-10 | — | — | CN | disclosed |